Engraftment and growth of transplanted pancreatic islets

PO Carlsson, A Andersson, C Carlsson… - Upsala journal of …, 2000 - Taylor & Francis
… with the observation that vascular endothelial growth factor … j3 and tumour necrosis factor-a
impaired islet function when … angiogenesis by growth factors: relevance to pancreatic islet

Human islets have fewer blood vessels than mouse islets and the density of islet vascular structures is increased in type 2 diabetes

M Brissova, A Shostak, CL Fligner… - Journal of …, 2015 - journals.sagepub.com
… Mouse pancreatic islets are highly vascularized with interactions between … vasculature is
primarily controlled by vascular endothelial growth factor-A (VEGF-A) and VEGF receptor 2 (…

Hepatocyte growth factor enhances engraftment and function of nonhuman primate islets

NM Fiaschi-Taesch, DM Berman, BM Sicari… - Diabetes, 2008 - Am Diabetes Assoc
… number of islets required for successful islet transplantation (5,6… of mHGF and hHGF on
vascularization of islet grafts in this … gene therapy vector for pancreatic islets in a transplant setting…

The pancreatic β-cell in the islet and organ community

D Eberhard, E Lammert - Current opinion in genetics & development, 2009 - Elsevier
… endocrine and nonendocrine islet cells are required for β-cell … Abbreviations: VEGF-A,
vascular endothelial growth factor-A; … Mature pancreatic islets are highly vascularized by a dense …

Determinants and dynamics of pancreatic islet architecture

MT Adams, B Blum - Islets, 2022 - Taylor & Francis
… , hyper-vascularized, islets, though no change in overall islet … indicate that islet architecture
is important for optimal islet … of human pancreatic islets has implications for islet cell function. …

The endothelial cells in islets of langerhans

G Mattsson - Upsala journal of medical sciences, 2005 - Taylor & Francis
vascular endothelial growth factor-A (VEGF-A) production in the … that a remaining normal
number of native pancreatic islets does not affect the formation of new blood vessels in an islet

[PDF][PDF] Mechanisms of angiogenesis process after pancreatic islet cell transplantation: role of intra-islet endothelial cells

S Narayanan, G Loganathan… - J Transplant …, 2017 - researchgate.net
… Using pancreatic islets as a model for vascularized tissue, this review will … ) Vascular
permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and …

Vasculogenic bio-synthetic hydrogel for enhancement of pancreatic islet engraftment and function in type 1 diabetes

EA Phelps, DM Headen, WR Taylor, PM Thulé… - Biomaterials, 2013 - Elsevier
… transplantation technique where pancreatic islets were … Because we hypothesized that
vascularization is critical for isletislets reduces the total number of donor islets required to …

[HTML][HTML] Matrix metalloproteinase-9 is essential for physiological Beta cell function and islet vascularization in adult mice

G Christoffersson, T Waldén, M Sandberg… - The American Journal of …, 2015 - Elsevier
pancreatic islets was described more than 15 years ago,1, 2 … implicated as important in
pancreas development and islet … by the release of vascular endothelial growth factor A (VEGF-A) …

Revascularization of pancreatic islet allografts is enhanced by α-1-antitrypsin under anti-inflammatory conditions

K Bellacen, N Kalay, E Ozeri, G Shahaf… - Cell …, 2013 - journals.sagepub.com
… AAT is known to induce vascular endothelial growth factor (… Pancreatic islets of Langerhans
are a highly vascularized … widely accepted that inflammation is required for angiogenesis. …