… To address the effect of weak TLR4 stimulation on virulence, we modified Y. … In summary,
a considerable deficit in response to LPS from Y. pestis grown at 37 C was common to cells …

… it is a very important virulence factor for pneumonic plague [12]… pestis synthesizes different
forms of LPS depending on host… pestis overcomes the mucosal barriers, it is phagocytosed by …

… pestis uses a variety of mechanisms to evade or overcome … pestis immediately begins to
produce tetra-acylated LPS, … pestis virulence factors that dampen cellular responses and …

… This work aims at unraveling the impact of particular LPS components on Y. pestis virulence,
… pestis pathogenicity factors responsible for systemic spread of bacteria in the host organism …

… pestis displays a quite unique set of virulence factors that allow successful infection of fleas
and subversion of immune responses in … a strong lipopolysaccharide response overcame Y. …

… lipopolysaccharide (LPS) as one of the pathogenicity factors of … pestis LPS may play a crucial
role in overcoming the defence … a good illustration of the fact that the active (endotoxic) LPS …

… of rough LPS is essential for Pla activity and virulence in Y. … inflammatory response and
establish fatal infection (41). … genes to coordinate virulence factor expression within global gene …

… uses a variety of different mechanisms to evade or overcome … of the pathogens’ major
virulence factors, plays a crucial role … pestis instantly begins to produce tetra-acylated LPS, which …

… pathogenic role than the additional virulence factors of Y. … innate immune response, we next
investigated the effects of LPS-… we also confirmed the strong antagonistic activity of LPS-37 (…

… immune response (36). In addition, a lack of O antigen and full … pOmpX-transformed colonies
with strong autoaggregation … pestis ompX gene is a novel essential virulence factor in a …