… expression of different virulence factors in response to changes in … Our results are in good
agreement with previously published … by human and murine cells in response to LPS from Y. …

… activates human plasminogen and is a central virulence factor … pestis to avoid innate immune
responses, and our results … LPS has a conical (concave) structure associated with strong …

… , the causal agent (Yersinia pestis) must rapidly sense and respond to rapid … of virulence
factors (such as the T3SS) are needed throughout the infection, whereas other virulence factors …

… mutations in LPS biosynthesis genes. The O antigen is an important virulence factor of many
… pseudotuberculosis rcsA resulted in a strong repression of biofilm formation in the flea [32, …

… ) LPS with random distribution of O antigen chain lengths. We demonstrated that these LPS
O antigen mutants were attenuated in virulence … that other Yersinia virulence factors depend …

… ) are central virulence factors for many pathogenic Gram-negative … To counter this, innate
immune responses can also sense … LPS-priming is not required to elicit a strong IL-1β response …

… , inflammatory responses are believed to be suppressed by Y. pestis virulence factors in …
(LPS) appears to antagonize TLR4, minimizing its role in defense against infection (14, 15). …

… Yersinia pestis has evolved means to overcome the fibrin‐… and an established central virulence
factor in plague [reviewed … Noteworthy is that, in contrast to the 25 C LPS, the 37 C LPS is …

… pestis virulence by evading recognition by the human receptor complex, we generated “humanized”
mice that … We were astonished to measure a significant response to LPS from Y. …

… Within this genus are Yersinia enterocolitica and the Yersinia … in the bacterium concerning
many virulence factors, including the … In many ways, the evolution of lipopolysaccharide (LPS) …