… area might represent the most “primitive source” of oligodendrocytes, a relic that lost its …
Alternatively, the first wave OPCs could be lost in the course of a (not yet demonstrated) …

… skin was suggestive of scleroderma. given the homogeniza… Delayed bone age and
good soft tissue shadows at 13 months of … include Werner syndrome (WS), WeidemannRautenstrauch …

… We also review the work of the Multiple Sclerosis Lesion Project, an international … and are
referred to as shadow plaques (Fig. 2). These shadow plaques are sharply demarcated areas …

… sclerosis is the commonest neurological disease affecting young adults. Whilst the initial
relapsing-remitting disease … diffusing from the cerebral meninges could be responsible, we have …

… SCLEROSIS AS AN AUTOIMMUNE DISEASE multiple sclerosis is the most important
inflammatory disease … , the inflammatory changes underlying multiple sclerosis do not seem to be …

… Much is known about the pathogenesis of amyotrophic lateral sclerosis (ALS); that is,
how the disease comes about in molecular terms. Virtually all the information has come from …

Multiple sclerosis (MS) is the most common chronic disabling neurological disease of young …
onset followed by steady progression (primary progressive multiple sclerosis, PPMS). …

… major advances in our understanding of multiple sclerosis (MS) heterogeneity, the substrate
… , shadow plaques are not limited to patients with early and relapsing MS and, in fact, can be …

… scleroderma or morphea,is a chronic disease ofunknown etiology in which circumscribed
skin areas undergo sclerosis … circumscribed scleroderma, mottled circumscribed scleroderma, …

… effects on the clinical progression of the disease. A better characterization of the
phenotype as well as the functions of senescent CD8 + T cells can be pivotal to prevent age-related …