Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit
ML Mohler, CE Bohl, A Jones, CC Coss… - Journal of medicinal …, 2009 - ACS Publications
… therapeutic potential of nonsteroidal tissue-selective androgen receptor modulators (SARMs)
a … Rapidly expanding knowledge of nuclear hormone receptor structure and function and …
a … Rapidly expanding knowledge of nuclear hormone receptor structure and function and …
Nonsteroidal selective androgen receptors modulators (SARMs): designer androgens with flexible structures provide clinical promise
TR Brown - Endocrinology, 2004 - academic.oup.com
… of nonsteroidal selective androgen receptor modulators (SARMs). Interestingly, this group
of investigators has discovered a series of novel derivatives of the nonsteroidal antiandrogens…
of investigators has discovered a series of novel derivatives of the nonsteroidal antiandrogens…
[PDF][PDF] Novel, non-steroidal, selective androgen receptor modulators (SARMs) with anabolic activity in bone and muscle and improved safety profile
J Rosen, A Negro-Vilar - Journal of Musculoskeletal and Neuronal …, 2002 - researchgate.net
… , is the development of selective androgen receptor modulators (SARMs) that can stimulate
… novel, non-steroidal, orally-active selective androgen receptor modulators (SARMs) that …
… novel, non-steroidal, orally-active selective androgen receptor modulators (SARMs) that …
Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs)
W Gao, JT Dalton - Drug discovery today, 2007 - Elsevier
… and marketing of selective estrogen receptor modulators (SERMs) in the … non-steroidal,
selective androgen receptor modulators (SARMs) is to achieve tissue-selective modulation of AR …
selective androgen receptor modulators (SARMs) is to achieve tissue-selective modulation of AR …
Anti‐androgenic effects of S‐40542, a novel non‐steroidal selective androgen receptor modulator (SARM) for the treatment of benign prostatic hyperplasia
H Nejishima, N Yamamoto, M Suzuki, K Furuya… - The …, 2012 - Wiley Online Library
… Selective androgen receptor modulators (SARMs) would provide alternative therapeutic
agent for androgen-related diseases. We identified a tetrahydroquinoline (THQ) derivative, 1-(8-…
agent for androgen-related diseases. We identified a tetrahydroquinoline (THQ) derivative, 1-(8-…
Development of selective androgen receptor modulators (SARMs)
… Most of the SARMs developed thus far are non-steroidal and have the ability to activate the
AR in muscle and bone, without accompanying activation or minimal activation of the AR in …
AR in muscle and bone, without accompanying activation or minimal activation of the AR in …
Analysis of the growing public interest in selective androgen receptor modulators
IV Efimenko, W Chertman, TA Masterson… - Andrologia, 2021 - Wiley Online Library
… Selective androgen receptor modulators (SARMs) are a … androgen receptors and displays
tissue-selective activation of … Rad 140 Nonsteroidal Selective Androgen Receptor Modulator …
tissue-selective activation of … Rad 140 Nonsteroidal Selective Androgen Receptor Modulator …
Selective androgen receptor modulators: current knowledge and clinical applications
ZJ Solomon, JR Mirabal, DJ Mazur… - Sexual medicine …, 2019 - academic.oup.com
… Selective androgen receptor modulators (SARMs) are small-molecule drugs that can
exert varying degrees of both agonist and antagonist effects on ARs in different tissues. Their …
exert varying degrees of both agonist and antagonist effects on ARs in different tissues. Their …
Bone anabolic effects of S-40503, a novel nonsteroidal selective androgen receptor modulator (SARM), in rat models of osteoporosis
K Hanada, K Furuya, N Yamamoto… - Biological and …, 2003 - jstage.jst.go.jp
… A novel nonsteroidal androgen receptor (AR) binder, S-… to develop selective androgen receptor
modulators (SARMs). We … a prototype for SARMs, which had unique tissue selectivity with …
modulators (SARMs). We … a prototype for SARMs, which had unique tissue selectivity with …
[HTML][HTML] Selective androgen receptor modulators as function promoting therapies
S Bhasin - The Journal of frailty & aging, 2015 - ncbi.nlm.nih.gov
… selective androgen receptor modulators (SARMs), a class of androgen receptor ligands that
bind to androgen receptors … non-steroidal SARMs, testosterone and steroidal SARMs have …
bind to androgen receptors … non-steroidal SARMs, testosterone and steroidal SARMs have …
相关搜索
- development of selective androgen receptor modulators
- selective androgen receptor modulator body mass
- selective androgen receptor modulator bone loss
- anabolic selective androgen receptor modulator
- selective androgen receptor modulator reduced impact
- selective androgen receptor modulator additive effects
- selective androgen receptor modulator preclinical characterization
- drug insight selective androgen receptor modulators
- therapeutic promise selective androgen receptor modulators
- functional limitations selective androgen receptor modulators
- safety profile selective androgen receptor modulators
- biological characterization selective androgen receptor modulators
- medicinal chemistry selective androgen receptor modulators
- therapeutic use selective androgen receptor modulators
- safety evaluation selective androgen receptor modulators
- clinical applications selective androgen receptor modulators