[HTML][HTML] SUMO 化通路及其抑制剂研究概述

于祥旭, 陆美玲 - Bioprocess, 2022 - hanspub.org
… The small ubiquitin like modification (SUMO) pathway is conserved in all eukaryotes and
plays a key role in gene expression regulation of cellular signal transduction and maintenance …

玉竹黄酮通过促进HNF1b 蛋白的SUMO 化修饰抑制分拣蛋白(sortilin) 介导的脂质积累及动脉粥样硬化

F LIU, S CHEN, X MING, H LI, Z ZENG… - Journal of Zhejiang …, 2023 - jzus.zju.edu.cn
… The SUMOylation of HNF1b protein enhanced the HNF1b-inhibited effect on sortilin expression
and reduced lipid contents in macrophages. PAOA-flavone treatment promoted SUMO-…

Sox 蛋白类泛素化修饰对神经发育和再生的影响

KC Chang - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… but inhibits neural differentiation (Lee et al., 2012). This study reveals a novel mechanism
for SUMO-… for the SoxC transcriptional network required for visual pathway development. J …

亨廷顿蛋白的翻译后修饰在亨廷顿病发病机制中的作用

Y Wang, F Lin, ZH Qin - Neuroscience Bulletin, 2010 - Springer
… The importance of this pathway in HD is further proved by the finding that inhibition of … will
be decreased by inhibiting the expression of the SUMO1 precursor or the activity of SUMO-1 …

活性氧调控蛋白质修饰影响肿瘤细胞行为机制的研究进展

易静, 杨洁 - 上海交通大学学报(医学版), 2012 - xuebao.shsmu.edu.cn
mechanisms involve in an inhibition of RhoA, HIF-1, NF-κB and other pro-survival signaling
pathways, … We ascertained for the first time that SUMO protease SENP3 is a redox sensing …

熱休克蛋白質九十在有絲分裂期間所扮演之角色

洪建中 - 2009 - nckur.lib.ncku.edu.tw
… of Sp1 and RNF4, here we found that this inhibition in the Sp1 level by RNF4 was reversed
by … E, b), and when we added the MG132 to inhibit the proteasome pathway, both of SUMO-1-…

PKR 通过SUMO 化修饰调控胰岛β 细胞P53 功能上调.

宛晓梦, 潘漪, 周晓艳, 高丽丽… - Progress in Modern …, 2016 - search.ebscohost.com
… -cell and the molecular mechanism of the inhibition of the proliferation of pancreatic 茁-cell. …
Characterization of the loss of SUMO pathway function on cancer cells and tumorproliferation[…

單胞綠藻SUMO E1 活化酶之基因選殖與蛋白質表現

黃俐嫻 - 臺灣大學微生物與生化學研究所學位論文, 2010 - airitilibrary.com
SUMO化修飾作用需經過一連串由SUMO E1活化酶,E2銜接酶,E3黏合酶… (sumo activating
enzyme subunit 1) 與SAE2 (sumo activating enzyme subunit 2) 兩個次單元體所組成,並負責SUMO

昆蟲桿狀病毒IE1 和IE2 間的交互作用在病毒初始感染的過程中扮演著關鍵性的角色

CY Liao - 2018 - ir.lib.ncu.edu.tw
… Then IE1 further triggers IE2 self-degradation through ubiquitination pathway to create an
environment suitable for DNA replication. Thus, this study delineates a complex story …

YB-1 致癌角色之探討: YB-1 誘發基因體不穩定性之分子機制

吳妍華 - 2012 - ir.lib.nycu.edu.tw
… Furthermore, to demonstrate the functional role and molecular mechanism of YB-1 in … as
a substrate for sumoylation pathway but also directly interacts with SUMO paralogs. Given that …