… channel. Fluid flow can activate stretch-activated calcium channel and/or L-type voltage-activated
calcium channel, … activation and ATP release, but flow-induced PGE2 release is not …

… by endosomal calcium channels called two-pore channels (TPCs) release genome, and
by blocking endosomal calcium channels TPCs, tetrandrine (Tet) prevented the release of the …

… Besides its direct action on K ATP channel, recent research had revealed that ATP also …
the activity of K ATP channel.21 Syn-1A can bind SUR1 and inhibit K ATP channel opening.22 …

… factor to govern KATP channel opening is the ATP/ADP ratio: … ATP-to-ADP ratios and open
in response to decreased ATP … channel activity (and any increase in intracellular ATP ([ATP]i) …

… In consideration of the mechanism for shear-stress-induced Ca2+ influx via ATP(adenosine
triphosphate)-gated ion channel P2X4 in vascular endothelial cells, a modified model is …

… (7) Excess ATP blocks pannexin channels, with more ATP release perpetuating the
NLRP3 inflammasome activation via open Cx43 hemichannels. Cell outline courtesy of Les …

… -pore membrane channel, is highly permeable to ATP and … greatly reduce hypotonicity-induced
ATP release. Treatment of … hypotonicity-induced ATP release depended on intracellular …

… In cultured spinal astrocytes the activation of purinergic ionotropic 2X receptors (P2XRs) by
ATP trigger the opening of Panx1-based channels, leading to ATP-induced ATP release and …

… For example, does Panx1 influence NPC biology through its channel function (ATP release,
ion fluxes), or protein-protein interactions, or a combination of both? While the jury is still out …

… channels, such as through the release of ATP. In the mouse CNS, Lezmy et al. (2021)
demonstrated that astrocytic release of ATP … , which subsequently affects neuronal ion channels. …