… factor-1琢(HIF-1琢) that activates transcription of many genes, … 目前已知的低氧调节基因主要
有血管内皮生长因子 (VEGF),… 导一氧化氮氧化合成酶(iNOS)和黄素氧化酶(HO-1)基因[15]. 这些…

… Activation of HIF and HIF dependent gene such as iNOS and … HIF-α 和它的下游 调控基因
VEGF 和iNOS 表达都增加.在相关的… 几项在探讨HIF-1 保护效应的研究都聚焦于HO-1 在 这种反应中…

… 素加氧酶( hemeoxygenase-1, HO-1)及转铁蛋白等表达的调控, … 性HIF-1 作为 缺氧诱导的核
转录因子, 参与了VEGF,ET-1 和 iNOs … of VEGF isoforms by epiphyseal chondrocytes during low-…

… HIF-1, a nuclear transcription factor, was discovered by Dr. … ), and free radical scavenging
(heme hydroxylase-1; HO-1). … /CBP, thus down regulating HIF-1-induced transcriptional activity. …

… by quantitative and staining assay at 5 day, Calcium … factor, HIF-1) 和血管内皮细胞生长因子
(VEGF),HO-1参与调控破骨细胞生成和骨再吸收;HO-1也能促进成骨细胞分化 [11-12] ,但HO-1在…

… VEGF,血管內皮生長因子;iNOS,誘發型一氧化碳合成酶;HO-1, … Prevention of HIF-1 activation
and iNOS gene targeting by low… gene enhancer at a site required for transcriptional activation. …

… 缺氧诱导因子-1(hypoxia inducible factor-1, HIF-1)是在哺乳动物体内广泛分布的核… factor,
VEGF),血红素加氧酶(hemeoxygenase 1, HO-1),诱导型NO合酶(iducible nitricoxide synthase, iNOS…

… HIF-1是由氧调节的α亚基和组成性表达的β亚基(芳香烃受体核转运蛋白, ARNT)构成的异二聚体
… 肝癌实体瘤内广泛低氧, HIF-1α过表达, 调节百余种下游靶基因, 编码EPO,VEGF,HO-1和iNOs,…

… , serotonergic synapse, HIF-1 signaling pathway, cholinergic … during this study are included
in this published article and its … response in spinal cord injury rats by activating Nrf2/HO-1 …