… autologous brain tumour aggregates are formed in a rotatory device which results in equally
sized spheroids even … The initial cell cultures prepared from the biopsy are free from necrotic …

… -invasive human brain tumour cells encircling autologous … brain tumour-derived cells with
dermal autologous spheroid. … brain tumourderived cultures with autologous connective tissue. …

… spheroids with the aim to standardize our invasion assay more stringently. The presence of
intraspecimen variation in spheroid … Chicoine M, Silbergeld DL: Assessment of brain tumor …

… the preparation and evaluation of primary cultures derived from brain tumour biopsies. (b) …
of heterologous and autologous ‘‘target’’ spheroids made for brain tumour invasion studies. (c) …

… Organoids and spheroids are different 3D cell culture models … such applications as cancer
cell migration and invasion [32]. … organotypic tumor spheroids retaining autologous immune …

… invasion is an important issue in tumour and developmental research. Here, we describe the
spheroid invasion assay in detail, a method for monitoring … , standard culture medium can …

… with brain tumor and tumor proliferation or tumor invasion in … The tumor spheroids were
cocultured with fetal rat brain cell … After a 2-week culture in a standard tissue culture incubator (…

… by a phenomenon referred to as autologous chemotaxis [58]. … directional migration of tumour
cells from the spheroid mass [134,… a glioma culture or from dissociated brain tumours—and …

… to demonstrate that spheroid cell cultures are useful for … They showed that invasion of the
spheroids by blood vessels … assay for brain tumours that are composed not only of tumour cells …

… and represents the most common primary malignant brain tumor in adults with a median
survival … -based 3D culture model of GBM spheroids interacting with brain endothelial cells in …