… blood-brain barrier (BBB), which is a dynamic, adaptable and highly complex natural barrier
to protect the brain… This paper reviews the drug delivery strategies across the BBB, including …

… delivering therapeutic genes across the bloodbrain barrier. Nanotechnology has emerged as
a possible solution, and several delivery … based gene delivery strives to transfer the product …

… blood-brain barrier is the interface through which the brain … network of brain endothelial
cells that forms blood vessels and … an obstacle for delivering treatments to the injured brain in …

… ; ④ inhibited the transporter to the brain by the blood brain barriers; ⑤ unable to … blood-brain
barrier (BBB) is considered the most challenging obstacle for delivering siRNA into the brain…

… the relaxivity for MRI, overcome the blood-brain barrier and enhance tumor-specific targeting,
hence improving the imaging quality and safety profile for precise and accurate imaging of …

… 血脑 屏障(blood brain barrier, BBB) 阻碍了许多外源性 物质向脑组织内渗透[7-8] ,也制约了…
Blood-brain barrier shuttle peptides: an emerging paradigm for brain delivery [J]. Chem Soc …

… effects on the blood-brain barrier. Since the prevention of blood-brain barrier disruption was
… practically feasible, because especially the controlled delivery of HES to the BBB would be a …

… brain edema, oxidative stress, and apoptosis, leading to disruption of the blood-brain barrier
(… the treatment of acute CNS injuries and drug delivery to the brain. A recent/ ongoing phase-…

… of new regulatory mechanisms and substances, as well as the emergence of new paradigms.
… APOE4 is less effective at removing Aβ from the blood-brain barrier (BBB) than other APOE …

… Immunotherapy, a new treatment paradigm, treats cancer … can enter the brain through the
broken blood-brain barrier. CNS: … Blood-brain barrier; BCSFB: Blood-cerebrospinal fluid barrier…