基因诊断在苯妥英治疗癫痫病中的应用

刘扬, 宋亚娟, 丁国华 - 中国临床药理学与治疗学, 2009 - manu41.magtech.com.cn
… The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement[
J… Dosage recommendation of phenytoin for patient with epilepsy eith different CYP2C9

[PDF][PDF] 丙戊酸钠基因组学的研究进展

周浔, 谭落娇, 赵宏宇, 高守红 - Journal of Pharmaceutical …, 2020 - yxsj.smmu.edu.cn
… its metabolism which is influenced by many factors. The gene … of genomics and clinical
treatment on valproic acid clinical … Associations of CYP2C9 and CYP2A6 polymorphisms with …

抗癫痫药的群体药代动力学与CYP450 基因多态性的研究进展

姜德春, 白向荣, 王育琴, 李林 - 中国临床药理学与治疗学, 2006 - manu41.magtech.com.cn
… The effect of genetic polymorphism of cytochrome P450 CYP2C9 on … polymorphisms of
CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy:…

CYP2C9 基因多态性及其功能意义研究进展

李智, 王果, 周宏灏 - 中国临床药理学与治疗学, 2008 - manu41.magtech.com.cn
… Flanking region polymorphisms of CYP2C9 and their … Japanese epileptic patients:genetic
analysis of the CYP2C9 … Pharmacokinetics of chlorpheniramine, phenytoin, glipizide …

[HTML][HTML] 两个重要的高血压个体化用药相关基因多态位点及检测方法的研究进展

魏晓纯, 何震宇 - Hans Journal of Biomedicine, 2024 - hanspub.org
… market, but there are polymorphisms in the drug metabolism … the two loci that have an
important influence on the efficacy of … 人群中CYP2C9多态性频率差异,欧洲各国人群的CYP2C9 * 2…

[PDF][PDF] 基因导向的个体化治疗

刘志艳, 杨兵, 赵荣生 - 临床药物治疗杂志, 2017 - lcywzlzz.com
Effect of CYP2C9 genetic polymorphism on the metabolism of flurbiprofen in vitro[J]. Drug …
phenytoin therapy for japanese pediatric patients with epilepsy based on CYP2C9 and …

CYP2C9, CYP2C19, CYP3A4 基因多态性对磺脲类降糖药代谢的影响

李赟, 何芳, 曾彩雯, 刘林林… - 中国临床药理学与治疗 …, 2012 - manu41.magtech.com.cn
… 已发现CYP2C9存在30种等位基因,分别 被命名为CYP2C9*1至… 野生型(CYP2C9*1),R144C
突变型(CYP2C9*2),I359L突变型(… Influence of CYP2C9 and CYP2C19 genetic Polymorphism on …

[PDF][PDF] 2021 年台灣腦中風學會與台灣癲癇醫學會之中風後癲癇治療指引

陳龍, 林秀娜, 陳志昊, 黃祐賢, 曾元孚, 鄭美雲… - 台灣中風醫誌, 2021 - vghtc.gov.tw
… 已和蛋白質結合 之phenytoin,增加血中phenytoin的游離濃度, … (CYP2C9), glibenclamide (CYP2C9)及
glipizide (CYP2C9)由 於… The ALDH2 rs671 polymorphism affects post-stroke epilepsy

[PDF][PDF] 丙戊酸个体化给药研究进展*

袁磊, 马慕白, 彭麒霖, 王晟鑫, 周伯庭 - 医药导报, 2017 - yydbzz.com
… (CYP2C9 ∗1/ ∗3)标准化丙戊酸血药浓度显著高于CYP2C9∗ 3 … phenytoin and valproic acid
in a child with refractory epilepsyInfluence of UDP-glucuronosyltransferase polymorphisms on …

CYP2C19 基因多态性对药物代谢的影响及其个体化用药

严非, 夏春华, 熊玉卿 - 中国临床药理学与治疗学, 2010 - manu41.magtech.com.cn
… Effects of CYP2C19 and CYP2C9 genotypes on pharmacoki… Formation of a dihydroxy
metabolite of phenytoin in human liver … about the effect of CYP2C19 genetic polymorphism on …