表現人類終端酶藉由表觀基因回復骨髓幹細胞多能分化性及抑制自然分化

陳俊利 - 2008 - tdr.lib.ntu.edu.tw
… in DNA methylation level as proved by a global CpG island … In mammals, DNA methylation
of cytosines in cytosine … mainly associated with development and cellular differentiation. This …

[PDF][PDF] 表观遗传学手册

T Tollefsbol - ecsponline.com
… of DNA methylation, which can also influence such processes as X chromosome inactivation
and cellular differentiation, is … immunoprecipitation (MeDIP) and the methylated-CpG island

CpG 甲基化降低是脊髓损伤后重要的表观遗传靶点

Z Wu, C Li, R Zhu, Y Cao, TC Chen… - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… , the density of CpG dinucleotides surrounding CpG islands was … Surprisingly, DNA methylation
was not associated with … only CHG demonstrated B-cell differentiation–related clustering, …

b-Boule 基因5′ 调控序列的克隆与睾丸组织DMR 甲基化分析

李明桂, 徐洪涛, 李隐侠, 于莎莉, 赵兴波, 潘增祥… - 中国农业 …, 2011 - chinaagrisci.com
… A novel requirement in mammalian spermatid differentiation for the … Incorrect DNA methylation
of the DAZL promoter CpG island … in mammalian cells. Nature Structural and Molecular …

前列腺癌相關之人類基因甲基轉移酶突變體的結構和生化研究

黃薰禾 - 2023 - tdr.lib.ntu.edu.tw
Mammalian DNA methylation is an epigenetic modification mechanism that plays key roles
in the regulation of various cellular … hypo-methylated regions (HMRs) at both CpG islands, …

3OST3B 與CDH3 基因於台灣乳癌檢體組織之甲基化變異及基因功能分析

黃國真, 陳小玲, 陳全木 - 2007 - people.dyu.edu.tw
… on the relation between aberrant DNA methylation in gene promoter … induction of Friend
erythroleukemia cell differentiation by 5-… of CpG islands exhibiting altered Methylation patterns(…

Dnmt1 通过Cdkn1a 甲基化调控脂肪分化的过程

杨益, 易凡, 张沛, 李华, 杜权 - 中国药学(英文版), 2017 - jcps.bjmu.edu.cn
… Although DNA methylation has been well studied in cancer and mammalian development[…
, and it mediates transcriptional silencing by methylating CpG island[20]. To understand the …

[HTML][HTML] 寻常型银屑病外周血单个核细胞和皮损组织表观遗传修饰异常的研究

苏玉文 - 2010 - cgl.org.cn
… To investigate the question whether there are any changes in epigenetic modifications in
psoriasis, we detected DNA methylation status, histone acetylation/methylation levels and …

芯片技术与肿瘤中DNA 甲基化研究

田筱青, 孙丹凤, 张燕捷, 房静远 - 遗传, 2008 - chinagene.cn
… inactivation, regulation of development and cell differentiation. Aberrant DNA methylation has
been linked … Isolation of DNA fragments associated with methylated CpG islands in human …

DNA 甲基化测序技术研究进展

袁明波, 叶国华, 杨丹, 宋冬雪 - 生物技术通报, 2024 - biotech.aiijournal.com
… promoted the development of epigenomics. This article reviews a series of DNA methylation
… It also introduces sequencing methods for locating DNA methylation at the single-cell level, …