SQSTM1/p62 在肌萎缩性侧索硬化和额颞痴呆发病机理中的作用

AD Foster, SL Rea - 中国神经再生研究(英文版), 2020 - sjzsyj.com.cn
Amyotrophic lateral sclerosis (ALS), the most common form of … a build-up of aggregated
TDP-43. However, upregulation of … triggers nuclear factor κBmediated pathogenic pathways. J …

DNA 可塑性与肌萎缩性侧索硬化症

D Penndorf, OW Witte, A Kretz - 中国神经再生研究(英文版), 2018 - sjzsyj.com.cn
… The pathophysiology of amyotrophic lateral sclerosis (ALS) is … the prevailing TDP-43 pathology
found in many ALS entities, … of other ALS-related mutations to a cytotoxic TE deregulation. …

肌萎缩侧索硬化症中NRF2 信号级联: 弥合前景与现实之间的差距

P Tarot, C Lasbleiz, JC Liévens - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… of the attempted clinical assays in amyotrophic lateral sclerosis. … ALS patients, suggesting
that deregulation of wild-type TDP43 … TDP-43 induced motoneuron-like cellular model of ALS

肌萎缩性侧索硬化的线粒体质量控制

B Khalil, JC Liévens - 中国神经再生研究(英文版), 2017 - sjzsyj.com.cn
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative … majority of ALS patients, suggesting
that deregulation and … Hence, we propose that TDP-43 induces excessive mitochondrial …

长链非编码RNA 作为神经退行性疾病的表观遗传调控因子

P Ruffo, F De Amicis, E Giardina… - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… that their deregulation could trigger neuronal degeneration … ’s disease AND amyotrophic
lateral sclerosis. Subsequently, we … TDP-43 and FUS proteins bind NETA1_2 to properly create …

细胞外囊泡在诊断和治疗中枢神经系统疾病中的作用

AA Shaimardanova, VV Solovyeva… - 中国神经再生研究 …, 2020 - sjzsyj.com.cn
… Whereas, adsorptive-mediated transcytosis is mediated by adsorption of cationic particles to
… of TDP-43, FUS, C9orf72, TDP-43 are characterized of amyotrophic lateral sclerosis (Saberi …

Cdk5 与神经退行性变核心的异常细胞周期激活

R Requejo-Aguilar - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… ’s disease, amyotrophic lateral sclerosis, and Huntington’s … , through STAT3-mediated
transcription of β-secretase gene (… system dysfunction and deregulation of molecular pathways …

微小RNA 在肌萎缩性侧索硬化动物模型中的表达及潜在的治疗方法

B Martinez, PV Peplow - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… animal models of amyotrophic lateral sclerosis showed a large … The TDP-43-Q331K model
shows many ALS-like features … of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). …

线粒体应激反应:“化身博士” 的神经元疾病

S Patergnani, G Morciano, M Carinci, S Leo… - 中国神经再生研究 …, 2022 - sjzsyj.com.cn
… ”, a mitochondria-mediated inflammatory response that is … also in amyotrophic lateral sclerosis
(ALS) and a spectrum of … the abnormal accumulation of mitochondrial TDP-43 due to the …

长链非编码RNA 在神经退行性疾病中的重要作用

W Xiong, L Lu, J Li - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… ’s disease, and amyotrophic lateral sclerosis. Finally, this review … of neurons and causes
abnormal nuclear-cytoplasmic … role of lncRNA-mediated mechanisms in the pathogenesis of …