靶向蛋白S-棕榈酰化修饰在T 细胞免疫疗法中的研究进展

孙丽婷, 张为国, 童玥 - 中国药科大学学报, 2024 - jcpu.cpu.edu.cn
… anti-tumor immune responses. A variety of T cell immune-related proteins are regulated by
… 免疫检查点 阻断(immune checkpoint blockade, ICB)疗法可用于 治疗结直肠癌,美国食品药品…

泛素化修饰和SUMO 化修饰在电离辐射诱导的DNA 损伤修复中的作用机制

张焕腾, 孙毓筱, 徐畅 - 国际放射医学核医学杂志, 2024 - ijrmnm.com
… , cell cycle, apoptosis and immune responses. When cells experience DNA damage,
ubiquitination modification and SUMOylation modification regulate the function and interaction of …

[HTML][HTML] NLRP3 炎症小体调控机制研究进展

刘雯, 郭文洁, 徐强, 孙洋 - 药学学报, 2016 - html.rhhz.net
… on the mechanisms of NLRP3 inflammasome regulation which mainly including NLRP3
priming, three protein complex assembly and regulation of NLRP3 inflammasome activation by …

[HTML][HTML] TANK 结合激酶1 在固有免疫应答中的作用及其泛素化调控

徐赫男, 李新宇, 方敏, 姜威 - 生物工程学报, 2021 - cjb.ijournals.cn
… Abstract: The innate immune system initiates innate immune responses by recognizing …
The finetuning regulation of TBK1 is essential to maintain immune homeostasis and resist …

[PDF][PDF] 开发针对泛素特异性蛋白酶的高质量化学探针

童宇峰 - 中国药理学与毒理学杂志 - cjpt.magtechjournal.com
… DNA damage repair, immune response, gene transcription, … regulated. Since
ubiquitination is involved in almost every … It was also proposed that the ubiquitinationdeubiquitination

[PDF][PDF] 焦亡在脓毒症中的研究进展

沈灵芝, 李莉, 严静 - 中华危重病急救医学, 2019 - researchgate.net
… syndrome caused by an abnormal host immune response because of infection. Pyroptosis is
… Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation […

[HTML][HTML] 锌指蛋白A20 对炎症反应和细胞凋亡的调控作用及其在炎症性肠病中的影响

季蓉, 吴焕淦, 施茵 - 世界华人消化杂志, 2014 - wjgnet.com
… : ubiquitination and deubiquitination. It can negatively regulate inflammation and apoptosis
… and other pathways as well as the negative regulatory effect of zinc finger protein A20 on …

[HTML][HTML] NLRP3 炎症小体激活的调控机制研究进展

刘峰, 庄万欣, 杨媛, 高成江 - 生物医学转化, 2024 - swyxzh.ijournals.cn
regulation and intervention of inflammasome activation processes are pivotal for sustaining
immune … recent progress in elucidating the regulatory mechanisms governing NLRP3 …

USP18 介导的蛋白质去ISG 化及其在结核病等传染病中的作用

张其奥, 王子路, 李佩波, 谢建平 - 遗传, 2023 - chinagene.cn
… is widely involved in immune responses, such as host … proteins and inhibit host immune
responses by suppressing the … and NEMO for deubiquitination through distinct mechanisms. Sci …

[PDF][PDF] 大黄鱼肿瘤抑制因子cylindromatosis (LcCYLD) 的

张萌, 罗云江, 姚翠鸾 - 水产学报, 2022 - aquaticjournal.com
… in innate immune signaling transduction in various cell types through negative regulation
of NF-κB … To investigate the role of CYLD in the immune response of large yellow croaker (…