天然膳食化合物作为抗阿尔茨海默病药物的遗传和表观遗传靶标

WO Castillo-Ordoñez, N Cajas-Salazar… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
DNA methylation causes direct changes to DNA molecules … all other of our tissues and cell
types. This way, genome-wide … underlie the molecular bases of diverse human diseases. This …

經低劑量地西他濱治療之急性骨髓性白血病細胞以非放射性同位素標定胺基酸細胞培養進行蛋白質體分析

GA Oswita - 臺灣大學毒理學研究所學位論文, 2018 - airitilibrary.com
… in AML cell lines and primary human AML cells. These effects … in genome-wide promoter
DNA methylation and re-expression … dynamic changes of chromatin modifiers in leukemia cells

正常组织与肿瘤组织中总体5hmC 和5mC 水平的变化程度与结直肠癌肿瘤发生及预后有关

Y Tian, A Lin, M Gan, H Wang, D Yu, C Lai… - Journal of Zhejiang …, 2017 - Springer
… of global DNA methylation and hydroxymethylation from normal to tumor tissues in colorectal
… Distribution of 5-hydroxymethylcytosine in different human tissues. J. Nucleic Acids, 2011:…

表現人類終端酶藉由表觀基因回復骨髓幹細胞多能分化性及抑制自然分化

陳俊利 - 2008 - tdr.lib.ntu.edu.tw
through epigenetic mechanism, including DNA methylation … purpose to have a BMSC cell
line with the potential of ESCs, … profile of 3A6 with various normal human tissues, MSCs and …

3OST3B 與CDH3 基因於台灣乳癌檢體組織之甲基化變異及基因功能分析

黃國真, 陳小玲, 陳全木 - 2007 - people.dyu.edu.tw
DNA methylation in gene promoter region and breast cancer tumorigenesis. Tumor and normal
tissues … -azadC, in breast cancer cell line MDA-MB-231, the methylation level of 3OST3B …

前列腺癌相關之人類基因甲基轉移酶突變體的結構和生化研究

黃薰禾 - 2023 - tdr.lib.ntu.edu.tw
… Mammalian DNA methylation is an epigenetic modification mechanism … of DNA methylation
patterns are dynamically regulated … and expressed at low levels in adult somatic tissues [29]. …

[HTML][HTML] DNA 甲基化在猪胚胎发育过程中的研究进展

甘建宇, 张芯, 蔡更元, 洪林君, 黄思秀 - 畜牧兽医学报, 2022 - xml-data.org
… This review describes the effects of DNA methylation on embryonic development from three
Dynamic DNA methylation across diverse human cell lines and tissues[J]. Genome Res, …

非CpG 甲基化降低是脊髓损伤后重要的表观遗传靶点

Z Wu, C Li, R Zhu, Y Cao, TC Chen… - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… or inflammatory cells. In summary, our work elucidated the dynamic pattern of DNA methylation
in … Abnormal DNA methylation in thoracic spinal cord tissue following transection injury. …

脑组织的表达数量性状遗传位点定位方法解析精神疾病遗传基础

C Liu - Neuroscience Bulletin, 2011 - Springer
… Two exon-array studies using multiple human tissues and cell lines both demonstrate that
at least 73% of human multi-exon genes are alternatively spliced and that similar tissues have …

多能性胚胎干细胞与DNA 甲基化的关系

汪若凤, 郭永洪, 田勤, 段维鸽 - 中华细胞与干细胞 …, 2019 - zhxbygxbzz.cma-cmc.com.cn
… engineering and regeneration of functional tissues and organs in vitro or in … DNA methylation
on embryonic stem cells, particularly focusing on the maintenance of embryonic stem cell