… This article reviews the mechanism of action of carmustine and some clinical applications …
卡莫司汀与亚硒酸钠联用 前列腺癌(Castration resistant prostate cancer, CRPC)是最常见的癌症,…

… of new prostate cancer cases increased rapidly in China. … androgen receptor antagonists and
interaction mechanism were … foundation for discovery novel androgen receptor antagonists. …

… as new PCa patients in 2012. Additionally researchers pointed out that prostate cancer is not
… Androgen receptor antagonists can be divided into two categories according to the structure…

… 雄性激素受體(Androgen receptor, AR)是已被廣為研究的分子.… cells into a malignant stage
or maintains prostate cancer cell … Here we provide a whole new mechanism through which …

… of anti-PCa drugs in the … of new anti-PCa drugs by deeply investigating the binding mode
between tetrahydro-pyrazolopyrimidines and androgen receptor and clarifying the mechanisms…

… DNA motifs recognized by human androgen receptor in prostate cancer[J]. … Androgen
receptor functions in cas⁃ tration-resistant prostate cancer and mechanisms of resistance to new …

… Escaping from androgen ablation therapy makes prostate cancer intractable. The androgen
receptor (AR) remains active … This new pathway might provide possible targets for treating …

… the underlying mechanisms of this cancer … new therapies for castration-resistant prostate
cancer have been proposed, such as androgen receptor antagonists, immunotherapeutic drugs, …

… acquired resistance. Metastatic castration-resistant prostate cancer is in critical need of new
… more agents which improved survival, including androgen receptor (AR)-targeted therapies (…

… There are several evidences have been shown that during androgen deprivation, the
androgen receptor (AR) cofactors can enhance the transcription activity of AR to activate the AR …