表观基因组可成为帕金森病的治疗标靶?

SV Hegarty, AM Sullivan, GW O'Keeffe - 中国神经再生研究(英文版), 2016 - sjzsyj.com.cn
… modes of epigenetic regulation is DNA methylation (Figure 1). … Histone acetylation and DNA
methylation are the most … In summary, small molecule epigenetic modulators, such as those …

表观基因组治疗神经变性

F Coppedè - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
DNA sequence, and include DNA methylation and hydroxymethylation, post-translational
modifications of histone … possible epigenetic marks of early-life exposure as well as epigenetic

胶质瘤表观遗传学治疗的研究进展

周俊虎, 康春生 - 药学进展, 2021 - pps.cpu.edu.cn
epigenetic phenomena, including DNA methylation, histone … Therefore, small molecule
inhibitors targeting epigenetic … of small molecule inhibitors targeting epigenetic regulators in …

神经退行性疾病表观遗传学研究中因果关系评估的观点

P Koulousakis, A Tiane, N Hellings… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… and epigenetic factors, such as DNA hypermethylation, deacetylation of histones, and …
Spatiotemporal control of epigenetic modulation in causality assessment can be mimicked …

天然膳食化合物作为抗阿尔茨海默病药物的遗传和表观遗传靶标

WO Castillo-Ordoñez, N Cajas-Salazar… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
… One epigenetic mechanism known as DNA methylation … to use small molecules that target
specific epigenetic enzymes … : natural products as epigenetic modulators a treatment strategy. …

环境富集诱导轴突再生-表观遗传机制

BL Tang - 中国神经再生研究(英文版), 2020 - sjzsyj.com.cn
… enrichment, include DNA methylation/demethylation and N6-… implicate epigenetic changes
in the form of enhanced histone … a short review of these findings, as well as other epigenetic

组蛋白甲基转移酶Ezh2 和Suv4-20h1/Suv4-20h2 在神经发生中的作用

CT Rhodes, CHA Lin - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… We present an overview of epigenetic mechanisms including … ) DNA methylation; (2) histone
post-translational modifications and … therapeutic applications of histone enzyme modulators. …

活动依赖性的基因组结构重塑在印记细胞中促进记忆的形成和回忆

A Marco - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
Epigenetic modifications alter chromatin structure and DNA … the DNA is blocked by methyl
molecules (ie, DNA methylation)… as transcription factors, epigenetic modulators and unique set …

DNA 甲基转移酶1 调节神经元的存活

J Symmank, G Zimmer - 中国神经再生研究(英文版), 2017 - sjzsyj.com.cn
… networks epigenetic mechanisms like DNA methylation and his… Interactions between DNA
methylation and histone modifi… Hence, the modulation of DNMT1 expression and function …

表观调控与神经干细胞分化

HL Tang, JH Zhu - Neuroscience Bulletin, 2007 - Springer
… Recent progress indicates that epigenetic modulation is … Major epigenetic mechanisms
include DNA methylation, histone … use of epigenetic regulations, such as DNA methylation, to …