… activity of the hormone receptor system. The purpose of … of estrogenic receptors (ER) in
adenocarcinomas and in other neoplastic (polyps) and nonneoplastic diseases of the large bowel…

… tissues including the colon. ERβ is the predominant estrogen receptor expressed in both
normal and malignant colonic epithelium. However, during colon cancer progression, ERβ …

… colon cancer cell lines and tumors 1 and estradiol was found to activate the growth of colon
cancer cell line in vitro,2, 3 an estrogen receptor has not been detected in human colorectal …

… been shown to lower incidence of colon adenocarcinoma. Collectively, these findings indicate
… Furthermore, in patients with inflammatory bowel disease (IBD) followed for more than 10 …

… bowel diseases (IBDs) are chronic disorders … of other female hormones in ovariectomized
mice receiving AOM/DSS resulted in increased number of colon polyps and adenocarcinomas …

… One section of rectal tubular adenocarcinoma showed strong positive nuclear and
cytoplasmic staining of ERβ (Figure ​2C). A few stromal cells, smooth muscle cells and vascular …

… Previous studies suggest that sex steroids influence colorectal cancer (CRC) carcinogenesis.
The oestrogen receptor β (ERβ) is the predominantly expressed ER in the colon and loss …

… and most potent estrogen in humans is 17β-estradiol (E2). Other natural estrogens
include … The estrogen receptor (ER) recognizes a molecule as estrogen based on its three-…

… In this study, an ERα exon-5 deletion variant was cloned from a colon adenocarcinoma of
a male patient. ERα variants have been reported in several normal and neoplastic tissues (63, …

… tamoxifen might increase the risk of gastric adenocarcinoma. … the effects of estrogen and
estrogen receptors (ERs) from … bowel disease [59], while it has been observed that estradiol …