DNMT1 依赖性调节皮层中间神经元功能和存活
D Pensold, G Zimmer-Bensch - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
… age-related changes in the DNA methylation profiles could … Dnmt1 depletion ameliorates
the mutant Huntingtin-induced … in combination with comprehensive functional characterization, …
the mutant Huntingtin-induced … in combination with comprehensive functional characterization, …
基于植物的突变体亨廷顿模型驱动的GTPCH 和DHFR 表达障碍的发现
J Xie, FS Kittur, CY Hung, TT Ding - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… Expression of mutant huntingtin exon-1 (mHttex1) affects both murine and plant C1 … the
results of altered DNA and/or protein methylation. Concerning DNA methylation, it is established …
results of altered DNA and/or protein methylation. Concerning DNA methylation, it is established …
亨廷顿病中的组蛋白甲基化: 二价启动子是否受损?
N Zsindely, L Bodai - 中国神经再生研究(英文版), 2018 - sjzsyj.com.cn
… Recently, we published the results of a comprehensive … expression of non-celltype-specific
genes and finally neurodegeneration. In a Drosophila model of the disease mutant Huntingtin …
genes and finally neurodegeneration. In a Drosophila model of the disease mutant Huntingtin …
来自亨廷顿病患者的诱导多能干细胞: 定义和纠正疾病相关改变的有希望的方法
A Fatima, R Gutiérrez-Garcia, D Vilchez - 中国神经再生研究(英文版), 2019 - sjzsyj.com.cn
… repeat in the exon 1 of the huntingtin (HTT) gene. 34 … DNA methylation and post-translational
modifications of histone proteins, which can directly contribute to aberrant gene expression …
modifications of histone proteins, which can directly contribute to aberrant gene expression …
揭示阿尔茨海默病中的DNA 甲基化: 基于阵列的人脑研究综述
VC Alves, E Carro, J Figueiro-Silva - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… DNA methylation in Alzheimer’s disease neuropathology. The examination of various brain
regions reveals distinctive DNA methylation patterns that associate … a comprehensive body of …
regions reveals distinctive DNA methylation patterns that associate … a comprehensive body of …
[HTML][HTML] 表观遗传修饰在神经退行性变性疾病中的作用研究进展
QU Wenzheng, Y ZHUANG… - Journal of Zhejiang …, 2021 - ncbi.nlm.nih.gov
… ’s disease, Parkinson’s disease, Huntington’s disease. Abnormally … DNA methylation inhibits
the expression of some DNA repair-related genes and affects the progression of Huntington’…
the expression of some DNA repair-related genes and affects the progression of Huntington’…
组织蛋白酶L 在阿尔茨海默病核层病变诱导中的调节作用
MI Islam, E Eftekharpour - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… While still a hotly debated topic, a large body of literature based on years of preclinical …
DNA hypermethylation is suggested to be responsible for nuclear factor erythroid 2-related factor …
DNA hypermethylation is suggested to be responsible for nuclear factor erythroid 2-related factor …
人干细胞来源的小胶质细胞将成为阿尔茨海默病研究必不可少的工具箱
T Liu - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
… in animal model, even in the large animals like pig and non-human primate. … DNA methylation
is a type of epigenetic modification that refers to the addition of methyl groups onto DNA at …
is a type of epigenetic modification that refers to the addition of methyl groups onto DNA at …
长链非编码RNA 作为神经退行性疾病的表观遗传调控因子
P Ruffo, F De Amicis, E Giardina… - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… Epigenetic changes ensure that differential expression patterns are inherited … : DNA
modifications (DNA methylation and hydroxy-methylation), histone modifications (histone methylation…
modifications (DNA methylation and hydroxy-methylation), histone modifications (histone methylation…
解读PGC-1α 在神经系统疾病中的作用: 从线粒体功能障碍到突触衰竭
JD Panes, A Wendt, O Ramirez-Molina… - 中国神经再生研究 …, 2022 - sjzsyj.com.cn
… to age-related pathologies are Alzheimer’s disease, Huntington’s disease… Interestingly,
upregulation in DNA methylation and … to extensive upregulation of neurotransmitterrelated genes …
upregulation in DNA methylation and … to extensive upregulation of neurotransmitterrelated genes …