针对阿尔茨海默病病因的双重靶向纳米方法
SD Hettiarachchi, RM Leblanc - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
… Tacrine and galantamine hydrobromide are the most popular acetylcholinesterase inhibitors
used … The in vitro BBB penetrability and the cytotoxicity of the NPs were monitored by a BBB …
used … The in vitro BBB penetrability and the cytotoxicity of the NPs were monitored by a BBB …
基于脂质体的药物递送作为阿尔茨海默病的潜在治疗选择
C Hernandez, S Shukla - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… inhibitors (donepezil, galantamine, … aggregation and β amyloid plaque formation. Other
study done by the same group to make a multifunctional nanosized liposomes to target β amyloid…
study done by the same group to make a multifunctional nanosized liposomes to target β amyloid…
间充质干细胞源性外泌体促进阿尔茨海默病小鼠神经发生和认知功能恢复
EE Reza-Zaldivar, MA Hernández-Sapiéns… - 中国神经再生研究 …, 2019 - sjzsyj.com.cn
… , galantamine (all of them are acetylcholinesterase inhibitors), … normal control (control)
group; n = 36 for β-amyloid group … by the cerebral accumulation and cytotoxicity of amyloid beta-…
group; n = 36 for β-amyloid group … by the cerebral accumulation and cytotoxicity of amyloid beta-…
Aβ 寡聚体与阿尔茨海默病.
刘志安， 林燕玲， 韩爱东 - Acta Scientiarum Naturalium …, 2022 - search.ebscohost.com
… Here we review the latest research progresses on β-amyloid … 酯酶的抑制剂donepezil,galantamine
和 rivastigmine,1 个NMDAR … (1-42)cytotoxicity and aggregation in vitro by glucose and …
和 rivastigmine,1 个NMDAR … (1-42)cytotoxicity and aggregation in vitro by glucose and …
tau 截短体与阿尔茨海默病的发病机制
D Chu, X Yang, J Wang, Y Zhou, JH Gu… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
… β-amyloid plaques and intracellular neurofibrillary tangles consisting of aggregated and …
of AD, including four cholinesterase inhibitors (Donepezil, Galantamine, Rivastigmine, and …
of AD, including four cholinesterase inhibitors (Donepezil, Galantamine, Rivastigmine, and …
天然黄酮类化合物靶向干预阿尔茨海默病的神经炎症
Q Zhang, Y Yan - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… hours) notably inhibited tau aggregation, reduced tau oligomer-induced cytotoxicity, regulated
tau … and BACE-1 and reduces the β-amyloid burden in an APP transgenic mouse model of …
tau … and BACE-1 and reduces the β-amyloid burden in an APP transgenic mouse model of …
丁酰胆碱酯酶在阿尔茨海默病中的作用及其抑制剂设计策略
邢帅帅， 孙昊鹏 - 药学进展, 2023 - pps.cpu.edu.cn
… similar to those of AChE inhibitors. This article has reviewed … 例如, AD 的一大病理特征即是
β-淀粉样蛋白(β-amyloid, Aβ)的… 认知状况.donepezil,galantamine 和 rivastigmine 均能够通过抑制…
β-淀粉样蛋白(β-amyloid, Aβ)的… 认知状况.donepezil,galantamine 和 rivastigmine 均能够通过抑制…
探討數種天然化合物對Aβ1-42 造成大鼠腦皮質神經細胞毒性之保護功效
邱肇祥 - 2013 - tdr.lib.ntu.edu.tw
… 三,β-類澱粉胜肽(β-Amyloid peptide, Aβ) 介紹 早期阿茲海默醫生所發現大腦中的類澱粉蛋白
斑塊,直到1980 中期被證實 出是由一種稱為β -類澱粉胜肽(β-Amyloid peptide, Aβ) 所聚集而形成…
斑塊,直到1980 中期被證實 出是由一種稱為β -類澱粉胜肽(β-Amyloid peptide, Aβ) 所聚集而形成…
[PDF][PDF] 阿尔茨海默病的可能药物靶点和临床治疗研究进展
毕丹蕾， 文朗， 熊伟， 申勇 - 中国药理学与毒理学杂志, 2015 - cjpt.magtechjournal.com
… 它们分别是他克林(tacrine),多奈哌齐(done⁃ pezil),加兰他敏(galantamine)和利凡斯的明 (rivastigmine…
Predominant loss of glutamatergic terminal markers in a β- amyloid peptide model of …
Predominant loss of glutamatergic terminal markers in a β- amyloid peptide model of …