超氧化物歧化酶1-肌萎缩侧索硬化症的认知障碍
I Martinelli, E Zucchi, C Simonini… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… research. Since the identification of superoxide dismutase 1 in 1993, the field of amyotrophic
lateral sclerosis genetics has … FTD or ALS, although neuropsychiatric symptoms are more …
lateral sclerosis genetics has … FTD or ALS, although neuropsychiatric symptoms are more …
MicroRNA 生物标记物在额颞叶痴呆症中以及区分阿尔茨海默病和肌萎缩性侧索硬化症
B Martinez, PV Peplow - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… of patients with genetic FTD. The large majority of sporadic … We performed a PubMed search
for original research articles … mutations found in the genes most involved in FTD, MAPT, GRN…
for original research articles … mutations found in the genes most involved in FTD, MAPT, GRN…
将蛋白质组学发现转化为治疗痴呆症药物的策略
A Halder, E Drummond - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… of genetic forms of FTD can be achieved by testing for … ’s TREAT-AD genetics score, which
combines studies from genome-… -scoring protein in our analysis, as expected given its FDA-…
combines studies from genome-… -scoring protein in our analysis, as expected given its FDA-…
脑源性无细胞DNA
D Southwood, S Singh, Z Chatterton - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… for genes known to harbor mutations (eg, EGFR) can detect bd… for the combined genetic and
epigenetic analysis of bd-cfDNA … population, this burden is only expected to increase. As the …
epigenetic analysis of bd-cfDNA … population, this burden is only expected to increase. As the …
OSMR 是介导肌萎缩侧索硬化炎症反应的潜在驱动因素
W Chen, S Jiang, S Li, C Li, R Xu - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… , in this study we used a network-driven gene analysis tool, … Next, we converted the data
into log2 and filtered out genes … work in this area is expected to increase our understanding of …
into log2 and filtered out genes … work in this area is expected to increase our understanding of …
蛋白质合成调节作为肌萎缩侧索硬化和额颞叶痴呆的治疗方法
SE Charif, MF Vassallu, L Salvañal… - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… We strive to highlight the importance of research on drugs that, … AD can be also produced
by the mutation of the gene for … In FTD, the most relevant genes related to the development of …
by the mutation of the gene for … In FTD, the most relevant genes related to the development of …
神经丝在肌萎缩侧索硬化症中的应用现状及展望
YM Falzone, T Russo, T Domi, L Pozzi… - 中国神经再生研究 …, 2021 - sjzsyj.com.cn
… neuroimaging investigations and genetic analysis are helpful … and several ALS-related genes
codify for proteins involved in … FTD, with higher concentrations in the former, is reported in a …
codify for proteins involved in … FTD, with higher concentrations in the former, is reported in a …
肌萎缩侧索硬化的动物模型: 模型有效性的比较
JR Morrice, CY Gregory-Evans, CA Shaw - 中国神经再生研究(英文版), 2018 - sjzsyj.com.cn
… : its relative ease of genetic modification; genes implicated in … This feature acts as a confounding
factor in studies which … -43, which is based on the introduction of human mutant TDP-43 …
factor in studies which … -43, which is based on the introduction of human mutant TDP-43 …
阿尔茨海默病中的Aβ 肽和tau 蛋白串扰
AR Roda, G Serra-Mir, L Montoliu-Gaya… - 中国神经再生研究 …, 2022 - sjzsyj.com.cn
… of genes involved in synaptic function and, more importantly, … the other hand, some studies
suggest that microglia could … , Pick’s disease, and FTD-P, among others. Although this is not …
suggest that microglia could … , Pick’s disease, and FTD-P, among others. Although this is not …
陶氏症治疗方法的新见解
… Reports demonstrated the shortest survival rate for FTD … of targeted genes through
transcriptional gene silencing. When it … ASO MAPTRx in AD, more preclinical studies are required …
transcriptional gene silencing. When it … ASO MAPTRx in AD, more preclinical studies are required …