表現人類終端酶藉由表觀基因回復骨髓幹細胞多能分化性及抑制自然分化

陳俊利 - 2008 - tdr.lib.ntu.edu.tw
… to epigenetic remodeling, we conducted a genome-wide analysis of DNA methylation between
… A global CpG island methylation profile analysis revealed decreased methylation level of …

[HTML][HTML] 组蛋白甲基化水平与骨关节炎病理发展的关联性

DU Xiaotian, H OUYANG - Journal of Zhejiang University (Medical …, 2019 - ncbi.nlm.nih.gov
methylation is a type of epigenetic modification, and the link between histone methylation and
osteoarthritis has also been revealed. In … Genome-wide association and functional studies …

骨质疏松症的全基因组关联研究进展.

曾海涛, 吴飞, 何启艇, 刘世清 - Chinese Journal of …, 2016 - search.ebscohost.com
… 全基因组关联分析( genome wide association study,GWAS) 通过扫描人类整个基因组, 找出对
人类复杂疾病或者性状有一定影响的基因或 基因组区域,它不再需要预先假设致病基因.过去 几年…

蠑螈肢體再生: 神經介導表現之組蛋白去乙醯化酶之角色與雙螢光嵌合體肢體再生模式之建立

王睦惠 - 2023 - tdr.lib.ntu.edu.tw
genomewide studies are needed to determine the extent and functions of epigenetic
Additionally, HDAC4 and HDAC6 expression shows a notable increase only at 24 hpa. (B) In …

ATAC-seq 在复杂疾病研究中的应用进展

陈敏, 张峥, 孟紫媛, 张学军 - 遗传, 2020 - chinagene.cn
… ATAC-seq is used to map chromatin accessibility genome-wide … a pro-inflammatory epigenetic
and transcriptional profile in lupus … landscape of articular knee cartilage reveals aberrant …

哺乳动物DNA 甲基转移酶DNMT1 和DNMT3 结构与功能的研究进展

王晨晨, 张凡丽, 陈珮琪, 翁思瑶, 王慧芳… - 生物技术 …, 2022 - biotech.aiijournal.com
… protein family involved in epigenetic modification,and DNMT1,DNMT2, … of mammalian DNA
methylation,and the role of DNA … Chromosomal instability correlates with genome-wide DNA

RBM4 藉由調控丙酮酸激酶之選擇性剪接促進間質性幹細胞之神經分化

蘇俊豪 - 2017 - tdr.lib.ntu.edu.tw
mRNA 的選擇性剪接對大腦的發育以及神經功能有重要的影響.RBM4可透過調控選擇性剪接
促進神經前驅細胞的分化及培養中神經細胞突觸的生長.本論文中,我進一步的探討RBM4在神經…

痛风的多组学研究进展

时文睿, 渠鸿竹, 方向东 - 遗传, 2023 - chinagene.cn
Genome-wide association study revealed novel loci which … Integrative genome-wide
association studies of eQTL and … Differential DNA methylation of networked signaling, …

利用特定環境蛋白誘導毛囊新生

范邁儀 - 2018 - tdr.lib.ntu.edu.tw
… Changes in transcriptional activity could also cause to genome-wide regulation of inhibiting
and active epigenetic features such as DNA methylation, histone modifications and changes …

转运RNA 衍生的小RNA 功能及其研究方法

马剑峰, 甘麦邻, 朱砺, 沈林園 - 遗传, 2021 - chinagene.cn
… Many studies have revealed that the expression of tsRNA is significantlyimportant role in
various biological processes by regulating transcript stability, protein translation and epigenetic