… Cycolphosphamide, itself causes liver toxicity and long term steroid treatment also causes
… Cytotoxic drugs for cancer treatment, depending on which cancer types and the policy for …

… Abstract Necrostatin-1 (Nec-1) is a small molecule inhibitor … phosphorylation of mitogen
activated protein kinases (MAPKs), … (ROS)-induced hepatotoxicity in acetaminophen-induced …

… and severity of hepatotoxicity of gefitinib. Ninety patients with non-small cell lung cancer were
included in the retrospective clinical study. Detailed hepatotoxicity induced by gefitinib and …

… phosphorylation of the signal molecules of mitogen-activated protein kinases (MAPKs) and
… pathway and glioma tumor growth in vivo via reduction of tumor cell proliferation and the …

… that were effective in reducing tumor burden without adverse events or renal or … small
molecules. Further optimization of FC-A or the development of client-specific small molecules could …

… BRAF基因位于人类7号染色体的q34,是EGFR信号通路KRAS下游丝裂原活化蛋白激酶(mitogen-activated
protein kinase, MAPK)通路的关键分子.BRAF基因编码出的丝氨酸/苏氨酸蛋白激酶…

… As previously reported, exposure to aflatoxin leads to hepatotoxicity, which … identify target
candidates for a given small molecule. The reliability of reverse … – Cell division protein kinase 2 …

… As with most small molecule therapies, Pt chemotherapy is not tumor specific and always …
by activation of protein kinases and caspases. Mitogen-activated protein kinase has been the …

… -terminal kinases (JNKs) are components of a classical mitogen activated protein kinase (…
On the other hand, the dose at which EGCG causes hepatotoxicity is controversial. Goodin …

… 素-6(interleukin-6, IL-6),肿瘤坏死因子-α(tumor necrosis factor-α, TNF-α)水平;检测各组细胞高
… protein kinase 1, RIP1),受体相互作用蛋白激酶3(receptor interacting protein kinase 3, RIP3);…