探討新穎Histone Deacetylase Inhibitor (HDACi), Aza-PBHA 在活體小鼠及離體CCD-966SK 細胞對於促進傷口癒合機制探討

林思杰 - 臺北醫學大學藥學系(碩博士班) 學位論文, 2012 - airitilibrary.com
Histone deacetylase inhibitors (HDACi) can suppress histone deacetylase function and …
Nowadays, HDACi are used in for cancer and inflammatory treatment. In this study, Aza-PBHA (…

探討Histone Deacetylase Inhibitor II 等藥物抑制人類單核球細胞(THP-1) 誘發第九型基質金屬酵素活化之機轉

林怡秀 - 臺北醫學大學醫學科學研究所學位論文, 2003 - airitilibrary.com
… According to previous experiments, we found that histone deacetylase inhibitor II (HDI II)
and the derivatives of caffeic acid: VC-1 showed obviously inhibitory effect on MMPs activation. …

ERMAs 與protopine 在癌細胞中引起細胞凋亡之機轉探討以及sorafenib 與MPT0E028 併用之抗癌效果

陳俊翰 - 國立臺灣大學藥理學研究所學位論文, 2012 - airitilibrary.com
carcinoma (RCC) and hepatocellular carcinoma (HCC). It has been reported that histone
deacetylase (HDAC) inhibitors… and to inhibit growth of HCC by inhibiting proliferation and tumor-…

探討新穎組蛋白去乙醯酶抑制劑MPT0B390 對賀爾蒙治療無效的攝護腺癌之治療效果與作用機制

王鈺茹 - 2013 - nckur.lib.ncku.edu.tw
… is no effective treatment to cure the malignant prostate cancer. Histone deacetylase is one of
… of lysine on histone. Previous studies indicated that HDACs were overexpressed on various …

AR42, QS-ZYX-1-61, 及erolotinib 和MPT0E028 併用之抗腫瘤藥效與機制探討

陳美全 - 2012 - airitilibrary.com
… anti-cancer therapy. In the first chapter, we reported a novel phenylbutyrate-derived histone
deacetylase (HDAC) inhibitor … to its ability to target both histone acetylation-dependent and -…

[HTML][HTML] 丙戊酸钠对人胆管癌细胞生长抑制作用及其机制

王兵, 李红波, 杨杰, 邹声泉 - 中华肝脏外科 …, 2016 - zhgzwkssxdzzz.cma-cmc.com.cn
Effect of sodium valproate on inhibiting the growth of human cholangiocarcinoma cells
and … Histone deacetylases and their inhibitors as potential therapeutic drugs for …

组蛋白去乙酰化酶抑制剂对多发性骨髓瘤细胞的杀伤机制及临床应用现状

苑冬阳, 高欣, 杨融辉, 张萌, 廖爱军 - 中国肿瘤临床, 2018 - cjco.cn
… 组蛋白去乙酰化酶抑制剂(histone deacetylase inhibitors,HDACis)具有较好的抗MM… histone
deacetylase inhibitor romidepsin for the treatment of refractory multiple myeloma [J]. Cancer

MPT0E028 在人類大腸直腸癌與B 細胞淋巴癌之抗癌機轉探討

黃瀚立 - 2015 - tdr.lib.ntu.edu.tw
… efficaciously, drug development is still an important issue in cancer therapy. Histone deacetylase
inhibitor (HDAC) has been an important drug target in recent years. Our lab cooperates …

[HTML][HTML] 组蛋白去乙酰化酶抑制剂联合免疫检查点抑制剂治疗肿瘤的研究进展

方晨, 王勇, 李勇 - Chinese Journal of Lung Cancer, 2021 - ncbi.nlm.nih.gov
… 然而,相当部分患者对ICIs无应答、产生耐药或用药后病情出现新进展的情况不容忽视 [3-5] ,研究
[6] 表明,ICIs联合表观遗传调控药物组蛋白去乙酰化酶抑制剂(histone deacetylase inhibitor, …

Cinnamophilin 等藥物抑制人類單核球細胞(THP-1) 誘發第九型基質金屬蛋白酵素活化之機轉探討

崔巧琪 - 臺北醫學大學醫學科學研究所學位論文, 2003 - airitilibrary.com
… compound isolated from Cinnamomum philippinense, presented significant inhibitory effect
on MMP-9 activation. We also found that histone deacetylase inhibitor II (HDI II), as a potent …