… receptor-dependent enkephalinergic pathways. Here we demonstrate the functional specificity
in vivo of human Opiorphin. The pain-suppressive potency of Opiorphin is as effective as …

… -mediated antinociception while µ-opioid agonists modulate the antidepressant potency
produced by δ-opioid agonists. In summary, opiorphin, is a systemically active key modulator of …

… The relatively weak antinociceptive effects of opiorphin could be due to its route of …
enkephalinergic pathways. This could result from a weak metabolic stability and/or bioavailability of …

… human opiorphin has antidepressant-like effect. The antidepressant-like effect of opiorphin
… the antidepressive effect of opiorphin is through opioid-dependent pathways. Endogenous …

… and human opiorphin are the only three natural enkephalin … by activating endogenous
opioid-dependent pathways. Opioid … of opiorphin on colonic contractions and antinociception are …

… duration of the antinociceptive action of opiorphin with reference … pathway contributes to the
antinociceptive effects induced by … This suggests that the natural dual inhibitor opiorphin may …

… Opiorphin is a naturally occurring potent analgesic human peptide. It protects enkephalins
… effects mediated via opioid-dependent antinociceptive pathways. Opiorphin analog should …

… In summary, opiorphin, is a systemically active key modulator of both pain perception and …
Human opiorphin, a natural antinociceptive modulator of opioid-dependent pathways. Proc …

… control of neurotransmission pathways of pain and in the modulation of cerebral structure …
Human Opiorphin, a natural antinociceptive modulator of opioid-dependent pathways. Proc …

… , that human opiorphin is “a natural antinociceptive modulator of opioid-dependent pathways”.
… The antidepressant-like effect of human opiorphin via opioid dependent pathways in mice. …