[PDF][PDF] 基于人胚胎干细胞的药物毒性测试替代法研究进展

贾栗, 彭辉, 赵增明 - 中国药理学与毒理学杂志, 2016 - cjpt.magtechjournal.com
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a
transcriptomics approac[J]. Arch Toxicol,2013,87(1):123-143. [4] Zhang D,Shadrin IY,Lam J,Xian HQ,…

诱导多能干细胞衍生的脑细胞, 类器官, 组装体和血脑屏障模型在理解酒精和麻醉剂诱导的脑损伤中的应用: 一个新的视角

X Bai - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… Likewise, in stem cell-derived human neurons treated with … induced neurotoxicity observed
in human stem cell-derived … /inhibitory imbalance and transcriptomic analysis reveals the …

甲状腺干扰物的发育暴露: 晚年大脑干细胞的错误编程?

P Vancamp, S Remaud - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… SVZ reorganization at the transcriptome level, and that any … in parallel to assess developmental
neurotoxicity (Additional … animal models and human pluripotent stem cell-derived brain …

脊髓类器官研究应用的现在与未来

G Zhou, S Pang, Y Li, J Gao - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… primarily derived from induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs)
due … Generation of a motor nerve organoid with human stem cell-derived neurons. Stem

间充质干细胞衍生的细胞外小泡通过神经保护和神经修复作为创伤性脑损伤的无细胞治疗

Y Xiong, A Mahmood, M Chopp - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… In this review, we summarize mesenchymal stem/stromal cell-derived extracellular vesicles
as a cell-free therapy for traumatic brain injury via neuroprotection and neurorestoration and …

人多能干细胞在环境污染物风险评估中的应用与展望.

杨仁君, 任悦, 沈素, 殷诺雅… - Asian Journals of …, 2020 - search.ebscohost.com
… cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles [J]. … Human
embryonic stem cell-derived test systems for developmental neurotoxicity: A transcriptomics

人类皮质类器官的生成, 特性和皮质发育畸形的疾病模型

XP Zhang, XY Wang, SN Wang, CY Miao - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… neurotrophic factor and glial cell-derived neurotrophic factor, TGFβ … the infection mechanisms
and neurotoxicity associated with the … The transcriptomic trajectories of the human brain …

间充质基质细胞作为传染病相关脑病辅助治疗的新观点

MN Lima, MC Barbosa-Silva… - 中国神经再生研究(英文 …, 2022 - sjzsyj.com.cn
… (BDNF), glial cell derived neurotrophic factor, and vascular … , neurotoxicity and changes
in neurotransmitter systems are … the activation of the glutamatergic system and expressed in …

脑类器官可作为神经系统疾病药物筛选的新工具

JQ Zhou, LH Zeng, CT Li, DH He, HD Zhao… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… , the development of a phenotypic analysis system with high… particularly regarding the
development of screening strategies … This paper reviews the development of brain organoids and …

载脂蛋白E 亚型对散发性阿尔茨海默病的影响: 超越淀粉样蛋白β 的作用

M Lozupone, F Panza - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… alleles on the astrocyte transcriptome appears to be modest … -mortem human brain, induced
pluripotent stem-cellderived cells… A human-induced pluripotent stem cell-derived endothelial …