… Impact of whole brain radiation therapy on CSF penetration ability of icotinib in … Survival
of patients with brain metastases from non-small cell lung cancer harboring EGFR mutations …

… metastases from non⁃small cell lung cancer(NSCLC). … of NSCLC with brain metastases
who received icotinib were re⁃ … EGFR mutations in patients with brain metastases from lung …

… ) showed that icotinib has a good efficacy and tolerability in … non-small cell lung cancer
(NSCLC) compared with gefitinib. … of EGFR mutation patients with and without brain metastasis (…

… receptor(EGFR), such as gefitinib, erlotinib and icotinib, achieve … , especially for those
harboring EGFR mutations. Furthermore, … with brain metastasis from non-small-cell lung cancer:A …

… the efficacy of icotinib combined with radiotherapy for asymptomatic brain metastasis (BM)
in … with epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC). …

… icotinib for patients with brain metastases from non-small cell … Gefitinib versus erlotinib as
first-line treatment for patients … advanced EGFR mutation-positive non-small-cell lung cancer. …

… Conclusions The clinical efficacy and adverse events of icotinib and gefitinib … Icotinib is as
efficacious as gefi⁃ tinib for brain metastasis of EGFR mutated non ⁃ small ⁃ cell lung cancer…

… with unresectable lung adenocarcinoma with EGFR mutation positive who … EGFR-mutation-positive
non-small-cell lung cancer (stage IIIB~IV) who received first-generation Icotinib was …

… of lung cancer is non-small cell lung cancer (NSCLC). The incidence of brain metastases …
的第一代TKIs有吉非替尼（Gefitinib）、厄洛替尼（Erlotinib）及埃克替尼（Icotinib），二代TKIs有阿法替…