… drew attention toward the immunogenicity of TNFi showed a … immunogenicity adequate
drug level measurements are essential. In this review these different aspects of immunogenicity …

… published guidelines relating to unwanted immunogenicity of monoclonal antibodies for in
vivo clinical use, outlining the mandatory assessment of immunogenicity for the approval of …

… This meta-analysis represents the most thorough review of immunogenicity to TNF inhibitors
in RA, IBD, and SpA. However, it does have some limitations. First, it unavoidably includes …

… This publication marked the beginning of the combined use of TNF inhibitors and csDMARDs,
mainly methotrexate, in the treatment of RA 81,82 . Methotrexate reduces immunogenicity …

… This may be a plea in favor of loading dose at initiation of treatment, and in fact this is the
proposed regimen for some TNF inhibitors, namely infliximab and certolizumab. …

… of TNF inhibitors has … immunogenicity. Because the amino acid sequence of mouse proteins
is usually different from their human counterparts, mouse proteins tend to be immunogenic. …

… The immunogenicity of TNF inhibitors is an important factor that may affect the tolerability
and long-term efficacy of these agents. Research suggests that the anti-TNF monoclonal anti…

… The discussion around immunogenicity has recently intensified with the … (with immunogenic
potential). In this review, we therefore examine the association between immunogenicity and …

… making interpretation of immunogenicity data from published … monitoring (TDM) and
immunogenicity testing have not been … relevance of TDM and immunogenicity testing of TNFis in …

… Currently, there are many indications about the use of immunogenicity tests to guide the
therapy, but information regarding how to implement it in clinical practice is needed. …