[PDF][PDF] Impaired monocyte‐macrophage functions and defective toll‐like receptor signaling in hepatitis E virus‐infected pregnant women with acute liver failure
Acute viral hepatitis resulting due to hepatitis E viral infection (AVH‐E) is often serious in
pregnancy and could result in acute liver failure (ALF). The role of monocytes and
macrophages (mono‐macs) in the pathogenesis of AVH‐E and development of ALF‐E in
pregnancy is unclear. We investigated the functions of mono‐macs in pregnant (P), AVH‐E
(n= 44), ALF‐E (n= 12), healthy controls (HC; n= 20) and compared with nonpregnant (NP)
AVH‐E (n= 10), ALF‐E (n= 5), and HC (n= 10). We also recruited non‐hepatitis E virus …
pregnancy and could result in acute liver failure (ALF). The role of monocytes and
macrophages (mono‐macs) in the pathogenesis of AVH‐E and development of ALF‐E in
pregnancy is unclear. We investigated the functions of mono‐macs in pregnant (P), AVH‐E
(n= 44), ALF‐E (n= 12), healthy controls (HC; n= 20) and compared with nonpregnant (NP)
AVH‐E (n= 10), ALF‐E (n= 5), and HC (n= 10). We also recruited non‐hepatitis E virus …
Impaired monocyte-macrophage functions and defective Toll-like receptor signaling in hepatitis E virus-infected pregnant women with acute liver failure.
RS Rashi Sehgal, SP Sharda Patra, P David… - 2015 - cabidigitallibrary.org
Acute viral hepatitis resulting due to hepatitis E viral infection (AVH-E) is often serious in
pregnancy and could result in acute liver failure (ALF). The role of monocytes and
macrophages (mono-macs) in the pathogenesis of AVH-E and development of ALF-E in
pregnancy is unclear. We investigated the functions of mono-macs in pregnant (P), AVH-E
(n= 44), ALF-E (n= 12), healthy controls (HC; n= 20) and compared with nonpregnant (NP)
AVH-E (n= 10), ALF-E (n= 5), and HC (n= 10). We also recruited non-hepatitis E virus …
pregnancy and could result in acute liver failure (ALF). The role of monocytes and
macrophages (mono-macs) in the pathogenesis of AVH-E and development of ALF-E in
pregnancy is unclear. We investigated the functions of mono-macs in pregnant (P), AVH-E
(n= 44), ALF-E (n= 12), healthy controls (HC; n= 20) and compared with nonpregnant (NP)
AVH-E (n= 10), ALF-E (n= 5), and HC (n= 10). We also recruited non-hepatitis E virus …
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