基于细胞的脊髓小脑性共济失调治疗策略: 更新

JS Correia, S Duarte-Silva, AJ Salgado… - 中国神经再生研究(英文 …, 2023 - sjzsyj.com.cn
… a long glutamine tract (polyglutamine) in the respective wild-type protein causing misfolding
… Alternatively, as previously observed in Huntington’s disease mouse models, pre-treatment …

GABA-A 强直亚基在亨廷顿舞蹈病和衰老过程中出乎意料的突触可塑性: 一个观点

A Rosas-Arellano, A Estrada-Mondragón… - 中国神经再生研究 …, 2018 - sjzsyj.com.cn
… disorder caused by a genetic mutation of the huntingtin … When mutant huntingtin (mHtt)
aggregates in medium sized spiny … degeneration and nuclear localization of mutant huntingtin in …

亨廷顿病动物模型中microRNA 表达的改变和潜在的治疗策略

B Martinez, PV Peplow - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
… miR-196a caused a decrease in mutant huntingtin mRNA and … (CAG, which encodes
glutamine) expanded repeat at exon 1, … medium spiny striatal neurons (MSN) and cortical neurons …

亨廷顿病中的线粒体: 发病机制和线粒体靶向治疗策略的意义

A Jurcau, CM Jurcau - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
Huntington’s disease is a genetic disease caused by expanded CAG repeats on exon 1 of
the huntingtin gene … In HD mice, there was a 6-fold decrease in PGC-1α in the medium spiny …

Machado-Joseph Disease 蛋白於人類神經腫瘤母細胞之研究

李彥賢 - 1999 - ir.csmu.edu.tw
… It is known that expanded polyglutamine tracts cause ataxin-… 內部除非是具有 NLS(nuclear
localization signal) 區域的全長… 疾病,如亨汀頓氏舞蹈症(Huntington′s Disease;HD),小腦脊 髓…

解读PGC-1α 在神经系统疾病中的作用: 从线粒体功能障碍到突触衰竭

JD Panes, A Wendt, O Ramirez-Molina… - 中国神经再生研究 …, 2022 - sjzsyj.com.cn
… Finally, we discuss recent studies showing novel specific … of a glutamine residue (CAG)
encoded by the huntingtin gene (… motor neurons in corticospinal tracts and induces a gradual …

牛膝多肽抑制谷氨酸电流在培养海马神经元发挥抗凋亡作用

RL Pan, WQ Hu, J Pan, L Huang, CC Luan… - 中国神经再生研究(英文 …, 2020 - sjzsyj.com.cn
… The extract of A. bidentata Blume roots contains polysaccharides, saponins, sterols, … ) and
glutamine (0.5 mM, Gibco). Half of the medium was replaced with fresh medium every 3 days. …

RI 理工学利用文献集(229)

山林尚道 - RADIOISOTOPES, 1986 - jstage.jst.go.jp
… up Regional Radiation-environment Monitoring System for Areas around Nuclear Plants …
glutamate synthase, glutamic acid, aspartic acid, asparagine, glutamine synthetase inhibitor, …