[PDF][PDF] 溶血磷脂酸及其受体在肾纤维化中的研究进展

肖欣, 魏佳莉 - 河北医学, 2021 - hbyxzzs.cn
Lysophosphatidic acid receptor antagonists and cancer:the current trends,clinical implications,and
trials[J]. Cells,2021,10(7):1629. [2] Meduri B,… implications in different diseases[J]. …

[HTML][HTML] G 蛋白偶联受体与酪氨酸激酶受体之间的信号交流在肿瘤治疗中的作用

陈璐瑶, 杨洋, 安输, 郭晓汐, 郝倩, 徐天瑞, 刘莹 - 2017 - html.rhhz.net
… 溶血磷脂酸受体(lysophosphatidic acid receptor,LPAR) 结合后… 球蛋白受体激酶A (atropomyosin
receptor kinase A,TrkA) 也可以… neuroprotective effects GABA activated GABA B receptors

前列腺素受体配体, 脂肪酸衍生物和相关酶抑制剂对神经轴突细胞的损伤/保护

NA Sharif - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… different types of membrane-bound phospholipids to lysophosphatidic acid (LPA; Figure
15A), … In disorders where prostanoids have damaging effects, the receptor antagonists have a …

[PDF][PDF] G 蛋白偶联受体在肝细胞癌中调控作用研究进展

彭文婷, 孙妩弋, 厉歆然, 孙家昌… - 中国药理学与毒理学 …, 2017 - cjpt.magtechjournal.com
Lysophosphatidic acid receptor expression and function in human … Lysophosphatidic acid
augments human hepatocellular carcinoma cell invasion through LPA1 receptor and MMP-9 …

MPT0E028 在人類大腸直腸癌與B 細胞淋巴癌之抗癌機轉探討

黃瀚立 - 2015 - tdr.lib.ntu.edu.tw
… various toxicity profile and side effects arise in the available clinical studies of HDAC
inhibition in the treatment of cancer. Since HDAC inhibitors exhibit their potency especially in …

巨噬細胞在腹膜纖維化中的角色

林紀均 - 2017 - tdr.lib.ntu.edu.tw
… In conclusion, our study implicated that macrophages have decisive effects on peritoneal
fibrosis but not through macrophage-myofibroblast transition (MMT) pathway. Crosstalk …

[HTML][HTML] 抗器官纤维化药物研究进展

任强, 张陆勇, 李政 - 药学学报, 2020 - html.rhhz.net
… RO6842262 (47)是溶血磷脂酸受体1 (lysophosphatidic acid receptor 1, LPA1R)的选择性
抑制剂, 它可抑制LPA介导的肺纤维细胞的增殖和收缩, 这有可能是一种治疗IPF的新方法 [73] .BMS-…

TWIK 相关双孔钾通道和神经保护

JA Lamas, D Fernández-Fernández - 中国神经再生研究(英文版), 2019 - sjzsyj.com.cn
… Similarly, lysophosphatidic acid (LPA) increased TREK1 currents in inside-out macropatches
(dose-dependently and reversibly) but had no effect when applied in outside-out or whole-…

CDP 胆碱促进多发性硬化髓鞘再形成: 临床试验的必要性

V Gudi, P Grieb, RA Linker, T Skripuletz - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… In this review, we summarise the beneficial effects of CDP-choline on biolipid metabolism
and turnover with regard to inflammatory and regenerative processes. We also explain …

G 蛋白偶联受体在血管发育中的作用

李方方, 李文庆, 荆清 - 遗传, 2013 - chinagene.cn
… 受体, 包 括溶血磷脂酸受体(Lysophosphatidic acid receptor, LPAR)和1-磷酸鞘氨醇受体(Sphingosine-1-phosphate
receptor, S1PR).目前研究表明该类GPCRs 与血管 发生密切相关[9,10]. …