… But a decade later, prescription opioid abuse and addiction had reached epidemic
proportions. In 2010, more than 16,000 people in the US died of an opioid painkiller overdose; in …

… The proportion of overdose cases of parecoxib was 50.00%, which was higher than 26.31% …
Patient controlled opioid analgesia versus non-patient controlled opioid analgesia for …

… Abstract: Opioid analgesics play an important role in pain management. While opioid
analgesics have been used to control various types of acute and chronic pain, they bring about the …

… about the potential risks of prolonged use of opioid medications with an emphasis on the
development of tolerance, poisoning, and fatal overdoses. The review was built through the …

… therapies exist to manage opioid withdrawal in infants, their efficacy and long-term sequelae
are controversial. Further, the opioids used to manage withdrawal symptoms are robustly …

… Use of opioid analgesics in the treatment of cancer pain:evidence-based recommenda⁃
tions … Management of Opioid Analgesic Overdose[J]. N Engl J Med,2012,367(2):146-155. [7] …

… Comparative study for analgesic effect on moderate or severe acute lower limb pain
between different combination of NSAIDs and opioids[J].Practical Journal of Cardiac Cerebral …

… β-EP is an endogenous opioid neuropeptide and peptide hormone, which is similar to
opioid drugs in its analgesic properties. It is an opioid receptor agonist and is the main …

… Current pain management methods are not well suited to handle long-term pain treatment, …
in short term use, such as addiction and overdose. New developments in pain treatment are …