… In accordance with this view, Rstn induced severe insulin resistance. … influence insulin
sensitivity. In the chapter one of this study, we found that Rstn expression was reduced by insulin-…

… mechanisms of … on insulin resistance and lipoprotein metabolism; glutamine level was
associated with PFOS, PFNA and DEHP exposure, which may be linked with alteration of insulin …

… improve insulin sensitivity and … insulin sensitivity and reduced adipose tissue inflammation
in a diabetic mice model.(20] XU17 (B), as a FABP4 inhibitor, showed strong anti-inflammatory …

近年, 代谢综合征(metabolic syndrome, MS) 及其高发病率严重威胁着人类的健康和生命. 代谢
综合征病因学的核心是胰岛素抵抗(insulin resistance, IR), 然而, 其相关机制并不是十分清楚, …

… for the development of insulin resistance22 and that insulin resistance and defective β-cell …
in waist circumference and suggested improvements in insulin sensitivity and β-cell function …

背景: 本研究的目的是考察铁螯合剂去铁酮对糖尿病肾病(diabetic nephropathy,DN)大鼠的作用
及其相关的机制. 方法: 32只雄性Wistar大鼠(体重180‐220 g,6周)被随机分为对照组,DN组以及…

… It is likely that NAFLD is the hepatic manifestation of metabolic syndrome where insulin
resistance is the main risk factor.2 Many recent studies have reported that the increase in the …

… 葡萄糖耐受不良(glucose intolerance) 及胰島素阻抗(insulin resistance), 伴隨著血液中瘦素(leptin), …
mice exhibited higher glucose intolerance and insulin resistance than obese mice; the …

… inflammation in skeletal muscle by epigenetic mechanisms and how the miRNAs are involved
in regulating inflammation and insulin resistance. Here… inflammation and insulin resistance …

… , we examine pathological mechanisms implicated in these diseases such as oxidative stress,
accumulation of misfolded proteins, inflammation, demyelination, death of neurons, insulin …