支链氨基酸代谢在阿尔茨海默病和其他代谢紊乱的发展中的作用

B Polis, AO Samson - 中国神经再生研究(英文版), 2020 - sjzsyj.com.cn
… malfunction, compromised energy metabolism, and chronic … Also, arginine metabolism is
dramatically altered in … of arginine and to increase nitric oxide (NO) production. These features …

神经系统炎症反应的代谢重编程: 炎症与新陈代谢之间的交叉作用

J Amo-Aparicio, CA Dinarello… - 中国神经再生研究(英文 …, 2024 - sjzsyj.com.cn
… mediators (inducible nitric oxide synthase and nitric oxide), and … of LDs is to store excess
energy in the form of triglycerides. … how changes in inflammatory response affect metabolism

线粒体功能障碍与质量控制: 蛛网膜下腔出血的核心

J Zhang, Q Zhu, J Wang, Z Peng, Z Zhuang… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
… dysfunction, impaired energy metabolism, and ionic imbalance; this mismatch of … In addition,
Drp1 is affected by various post-transcriptional modifications. After SAH, excess nitric oxide

小胶质细胞耗竭作为一种治疗策略: 多发性硬化模型中的朋友还是敌人?

VSBW Mancini, AA Di Pietro… - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… the astrocyte-secreted extra-cellular matrix … energy demand and causes poor axonal
transport, especially in mitochondria, which leads to axonal dysfunction with metabolic alterations

二甲双胍有望用于治疗神经系统疾病: 生物标志物指导的治疗

A Loan, C Syal, M Lui, L He, J Wang - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… by correcting their perturbed energy metabolism. However, … that specific mitochondrial
molecular alterations are potential … NF-κB, IL-1β and inducible nitric oxide synthase levels in the …

脊髓损伤后的常驻免疫反应: 星形胶质细胞和小胶质细胞的作用

S Brockie, C Zhou, MG Fehlings - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… Microglia regulate energy metabolism and debris clearance … , and nitric oxide are all produced
by astrocytes to affect changes … With excessive and prolonged synaptic glutamate binding, …

干细胞治疗缺血性脑卒中多层组学研究的优势

Y Wang, C Chang, R Wang, X Li, X Bao - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
Excessive glutamate release in the synaptic cleft causes … of proteases, lipases, nitric oxide
synthase, and endonuclease, … in gene expression, protein profiles, and metabolic changes of …

认知障碍性疾病中线粒体稳态的最新评估方法

W You, Y Li, K Liu, X Mi, Y Li, X Guo, Z Li - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… ATP production can indicate the overall energy metabolism of … Nitric oxide functions as a
signaling molecule, but the … We can use APEX or other methods to capture the changes in …

线粒体应激反应:“化身博士” 的神经元疾病

S Patergnani, G Morciano, M Carinci, S Leo… - 中国神经再生研究 …, 2022 - sjzsyj.com.cn
… defects, and mitochondrial DNA alteration. Cells engage in different … Profound metabolic
signatures have been unveiled in mice … Here, we confirm the excessive presence of mitophagy …

泛酸激酶相关神经变性的精准医学

M Álvarez-Córdoba, M Villanueva-Paz… - 中国神经再生研究 …, 2019 - sjzsyj.com.cn
… The defective PANK2 enzyme is predicted to impair the biosynthesis of CoA, resulting in a
myriad of metabolic alterations including deficient energy production, impaired biosynthesis …