靶向tau 淀粉样蛋白聚集的小分子

Z Manglano-Artuñedo, S Peña-Díaz… - 中国神经再生研究(英文 …, 2024 - sjzsyj.com.cn
… AD belongs to a group of heterogeneous and … intrinsically disordered protein that contributes
to microtubule stabilization and plays an important role in axonal transport. The tau protein

不要诅咒脊髓的黑暗: 点亮TDP-43

K Asakawa, H Handa, K Kawakami - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
… TDP-43 is an evolutionarily conserved heterogeneous nuclear ribonucleoprotein that
regulates … is prominent in the cytoplasm and mediated by the C-terminal intrinsically disordered

α-突触核蛋白聚集体的亚细胞定位及其与膜的相互作用

F Miraglia, A Ricci, L Rota, E Colla - 中国神经再生研究(英文版), 2018 - sjzsyj.com.cn
… Soluble cytosolic αS has been described as an intrinsically disorder protein due to an …
Thus the heterogeneity of αS toxic species, that is coming to light with recent findings shows …

[PDF][PDF] 艘van Rayment Clyde A. Smith

RG Yount - 1996 - academia.edu
… is responsible for the molecular basis of muscle contraction. This is consistent with recent …
Microheterogeneity around the reactive lysine residue in the myosin heavy chain from rabbit …

短肽的长话: 裂解特异性tau 抗体的治疗功效

G Amadoro, V Latina, P Calissano - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
… , highly flexible, intrinsically disordered protein which is … Tau primary structure includes
three different regions designed … heterogeneous features which involve different, both intrinsic

肌病和运动神经元变性中的Matrin-3 功能障碍

C Ward, UB Pandey - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… mainly of intrinsically disordered regions, the protein is … the molecular basis of disease-causing
mutations associated with distal myopathy and ALS. Expression of MATR3 fusion protein (…

调节神经元生物能是治疗神经退行性疾病的潜在策略

IG Onyango, JP Bennett Jr, GB Stokin - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
… , and amyotrophic lateral sclerosis are a heterogeneous group of debilitating disorders with
… distinct molecular mechanisms and clinical manifestations with abnormal protein dynamics …

α-突触核蛋白低聚物和原纤维: 突触核蛋白疾病中的犯罪伙伴

A Bigi, R Cascella, C Cecchi - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… αS is a 14-kDa intrinsically disordered protein first … Their heterogeneity is essentially associated
with differences … , as well as of the molecular mechanisms of their spreading, and of the …

神经棘红细胞增多症的临床及遗传特征

L Zhang, S Wang, J Lin - 中国神经再生研究(英文版), 2013 - sjzsyj.com.cn
… Here, neuroacanthocytosis, its clinical features and its potential molecular basis are …
striatum decreased, and the dopamine transporter protein binding rate of the striatum and the …

單分子量測系統與關聯分析之應用

楊禮綾 - 2009 - tdr.lib.ntu.edu.tw
… (A) Molecular mechanisms that might lead to fluorescence … Free ThT molecules in solution
though less fluorescent might … be confused as the heterogeneous fibril structures. To solve this …