… Ryuichi Nishinakamura is to understand the molecular mechanisms underlying kidney
development and to utilize this knowledge to rebuild the kidney from pluripotent stem cells. He …

… clinical application of cellular therapy for the repair of spinal … For example, multipotent neural
stem cells isolated from … vitro alters the extent and molecular basis of neurite outgrowth. Dev …

… in clinical situations, and there was a report that even induced pluripotent stem cells derived
… Our lab is now delving into detailed molecular mechanisms of IGF-1-mediated NSC survival …

… pluripotent stem cells can be developed into the precursor cells of each neural cell type at
the site of spinal cord injury… Nevertheless, ESC grafts will not achieve clinical use until their …

… to contribute to the molecular basis behind PD pathogenesis (… ’s disease using induced
pluripotent stem cells (iPSCs). In … “PD in a dish” also presents other clinical applications. It may …

… Another cell type involved in these processes is the multipotent neural stem cell (NSC), which
is still … remyelination process in adulthood involves the same molecular mechanisms as …

… pluripotent stem cells (iPSCs) appear to have lower ethical and immunogenic concerns
than other stem cells… and may engage distinct molecular mechanisms. Overexpression of a …

… cells, induced pluripotent stem cells, bone marrow … Following the requirements for clinical
application, we inde… of underlying molecular mechanisms remain incompletely understood. …

… been significant progress in the field of cell-based therapies, with the clinical application for
SCI, … in phase II of the clinical trial. Stem cells (eg., induced pluripotent stem cells, fetal stem …

… pluripotent stem cell-derived neural stem cell transplantation for treatment of spinal cord
injury, … Figure 1 Schematic illustration of the potential clinical application of iPSC-derived NSC …