基于siRNA 的脑出血疗法: 药物输送系统的挑战和进展

DA Almarghalani, SHS Boddu, M Ali… - 中国神经再生研究 …, 2022 - sjzsyj.com.cn
… Efficient delivery of siRNA via nanoparticles emerged as a … various viral and nonviral delivery
systems, including different … a vector for brain gene therapy by integrating into the host cell …

非病毒的caspase-3 siRNA 纳米粒子基因治疗可保护损伤的视神经

M Tawfik, X Zhang, L Grigartzik… - 中国神经再生研究 …, 2021 - sjzsyj.com.cn
gene therapy may rescue cell death after central nervous system damage. We developed a
novel, non-viral gene therapy to block caspase-3 gene … polybutylcyanoacrylate nanoparticles

基于脂质体的药物递送作为阿尔茨海默病的潜在治疗选择

C Hernandez, S Shukla - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… as a component of nanoparticle drug delivery; due to their … to treat areas of the central nervous
system. Systemic drugs … viral fragments along with a nonviral transporter. Pseudo virions …

遗传性神经发育障碍的产后治疗方法

G Levy, B Barak - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
… As a result, gene delivery into the CNS is largely dependent … of the therapeutic vector into
specific brain regions, eliminating … systemic delivery of lipid nanoparticles and other non-viral

抗脑部肿瘤纳米药物的研究进展

郑雅丹, 康子瑶, 王纯, 刘阳 - 药学进展, 2021 - pps.cpu.edu.cn
… based non-viral gene and drug delivery systems for brain cancer[J]. … and challenges in
developing nanoparticle- mediated drug delivery systems for the treatment of brain tumours[J/ …

改变新陈代谢以延长寿命

J Pessoa, AI Duarte - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… of the central nervous system, culminating in the arousal of neurodegenerative … non-viral
alternatives for gene delivery exist and include cationic lipid micelles and encapsulation inside

胶质细胞源性神经营养因子和细胞重编程对海马相关神经系统疾病的治疗潜力

P Chiavellini, M Canatelli-Mallat, M Lehmann… - 中国神经再生研究 …, 2022 - sjzsyj.com.cn
… We highlighted the most salient reports focusing on GDNF gene therapy as a … Non-viral
gene delivery vehicles, such as naked DNA, RNA, liposomes, and nanoparticles, can harbor …

非病毒脂质体载体转导脑源性神经营养因子可靶向透过血脑屏障

Y Xing, C Wen, S Li, Z Xia - 中国神经再生研究(英文版), 2016 - sjzsyj.com.cn
… Liposomes are a new type of non-viral vector, able to carry … results provide an experimental
basis for targeted gene therapy. … the treatment of central nervous system diseases. …

纳米微球携神经营养因子3 转染许旺细胞修复坐骨神经缺损

H Zong, H Zhao, Y Zhao, J Jia, L Yang, C Ma… - 中国神经再生研究 …, 2013 - sjzsyj.com.cn
… effects on nervous system development. It is … non-viral gene delivery vectors still remains a
great challenge. In this study, we reported a new gene delivery vector based on nanoparticles

基因疗法修复脊髓损伤: 临床前研究的系统综述和meta 分析

CJ Cunningham, M Viskontas, K Janowicz… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… approach showing promise is gene therapy. In this systematic … Non-viral vectors including
liposomes and nanoparticles … in the CNS or primary sensory neurons and glial cells at the …