… that oxidative stress could be a cause of the conformational … 3-nitrotyrosine (a product of
protein nitration) and the activity and … approach for AD, rather than relying on antibiotic treatment. …

… In this perspective, I will discuss recent evidence supporting that … Studies of protein aggregation
have historically been … cellular dysfunctions such as oxidative stress and impairments of …

… 1% of brain protein that can both ligate ubiquitin to proteins and … Oxidative modification and
down-regulation of UCHL1 has been … Another approach is to replace inactivated UCHL1 in …

… cells in the brain are highly susceptible to oxidative stress and … the best therapeutic
approach. This include traumatic … as a large precursor protein that needs further processing by …

… diseases such as oxidative stress, accumulation of misfolded … of this novel perspective into
future drug development … and microglial activation in Alzheimer disease: where do we go from …

… system is vulnerable to oxidative stress in brain aging, resulting … in protein oxidation is still
unclear and will require further … these neurodegenerative diseases from different perspectives. …

… in cellular components such as protein, lipid and DNA. … in studies related to oxidative stress
and neurodegenerative … From our perspective, the inhibition of p53 acetylation could be …

… thoughts and perspectives on future research about these … Although tau is predominantly an
intracellular protein, many forms … Ser400 sites phosphorylated in Alzheimer disease brain. J …

… lines: electrophysiological perspectives of future studies … The latter causes heavy oxidation
of numerous proteins, … sites) that are linked to the protein aggregation into tangles in the brain. …

… Another approach is reducing the activity of glutamate. In this … of oxidative stress has also
been confirmed by several studies… in the treatment of depression in Alzheimer disease patients: …