… insolubilization and aggregation of brain proteins and plays a … nervous system, protein
glycation induces oxidative stress, … and is considered a promising approach for the future. …

… temporal lobe of the AD brain compared to normal control tissue. … Whilst mRNA and protein
studies of GluN1 have been … offers a promising new approach to targeting the glutamatergic …

… Because of similarities with human brain anatomy and … activity, but when cells are exposed
to increased levels of oxidative … diseases, for instance by examining the role of prion protein …

… are reported to cause oxidative damage and mitochondrial … Proteostasis refers to the balance
of proteins that is needed … Following the study, a similar approach was used to screen a …

… on future perspectives and propose potential treatment … Studies demonstrated that vascular
oxidative stress can be … and neurovascular dysfunction in Alzheimer disease. Nat Rev …

… in a complex scenario, difficult to approach in a simple way. … counteracts neuroinflammatory
and oxidative stress-related … astrogliosis in mouse models of Alzheimer disease. PLoS One 7:…

… The cellular prion protein (PrPC), a cell surface glycoprotein … in the cellular response against
oxidative stress. Another … Finally, our approach can be useful for further development of …

… In this perspective, after a brief description of the available … , and in the brain of animal models
of neurodegeneration. … against oxidative damage, although these studies are mainly from …

… protein aggregate type, encompassing a range of proteins … involving mitochondrial dysfunction
or oxidative stress (Figure 1). … ) A novel approach to Parkinson’s disease treatment with a …