… TRPV1 is involved in the pathological processes of both chronic pain and depression,
which have similar pathobiological pathways in neuroinflammation and overlap in their clinical …

… that P2X receptors mediate in neuropathic pain might shed light … by which P2X receptors
contribute to in neuropathic pain and … P2X receptor channels in chronic pain pathways. Br J …

… receptors, the P2X receptor is a ligand-gated ion channel, and plays an important role in
visceral pain[11]. … neurons suppressed neural pathways in the cerebral cortex pain region via …

… cortical pathway … chronic pain involves the upregulation of ion channels and the subsequent
hyperexcitability of DRG neurons, which richly express voltage-dependent calcium channels …

… The P2X receptor is a ligand-gated ion channel that plays an important role in visceral pain,
… of a signal conduction pathway and regulated pain perception in the cerebral cortex. Recent …

… -injury responses such as chronic pain states. Several SGCs, … Through expression of a
number of receptors and channels, … communication by P2X receptors, NMDA receptors and gluta…

… natural aging, mental illness, chronic pain and pathological states … distinct receptor classes;
P1, P2Y and P2X receptors. P1 … receptors are generally associated with cell death pathways, …

… mechanisms that regulate SGCs during chronic pain. Finally, we … : ionic receptors (P2X
receptors) and metabolic receptors (… -cytokine-receptor signaling pathway can achieve feedback …

… receptor potential vanilloid type 1, purinergic P2X purinoceptor 3 and acid sensing ion channel
… upregulation of P2X receptors on thin fiber afferent nerves and therefore exaggerate the …

… of neuron plasticity in chronic pain. The excitatory amino acid … P2X receptors in peripheral
neurons. Prog Neurobiol, 65(2):… receptor activity via a PKA signaling pathway in a visceral …