… of perforin and granzyme B in PBMCs was detected by flow cytometry, and then the difference
of immune function … Results The levels of perforin and granzyme B in CD8+ T cells and NK …

Cholangiocarcinoma-derived exosomes inhibit the antitumor activity of cytokine-induced killer
cells by down-regulating the secretion of tumor necrosis factor-α and perforin | Journal of …

… Previous studies have shown that NK cells can use the cytolytic proteins, perforin and
granulysin to … NK cells use the cytolytic proteins, perforin and granulysin for direct killing, and the …

… 亚群比例,并且提高脾脏T淋巴细胞分泌细胞因子穿孔素(Perforin),TNF-和IFN-γ的能力.但是CBPA对
… 中细胞毒性因子包括颗粒酶B(GzmB)和Perforin的水平显著增加.这些炎性细胞因子相互协调…

… 其中球状蛋白成孔毒素中的两大家族, 胆固醇结合 细胞溶素(Cholesterol-dependent cytolysins,
CDCs) 和攻膜复合体/ 穿孔素超家族(Membrane attack complex/perforin superfamily, MACPF…

… perforin- nocked out mice, and the functional domains of perofrin protein. In this study, we
combined survivin promoter and perforin codeing sequence to construct a perforin … that perforin …

… of perforin and granzyme B protein, and further determine the relationship between PRF1
gene variants and cytotoxic T lymphocyte/natural killer (CTL/NK) cell function in … Perforin and …

… 小鼠模型 和HLH患儿情况相似,从重到轻是perforin,Rab27a, syntaxin一11;检测模型病毒负荷量
,… 然而P小/一的小鼠不出现T细胞耗竭的 情况,可能是perforin和syntaxin一11的缺陷影响不同的…

… Structural and functional analysis of perforin mutations in … Reduced incidence and
delayed onset of diabetes in perforin-… Variations of the perforin gene in patients with multiple …

… was prepared by immobilizing perforin aptamers on the … aptamers, perforin and antibodies
formed a sandwich structure, … achieve the identification of perforin and quantitative detection. …