Perspectives on cancer chemoprevention research and drug development

GJ Kelloff - Advances in Cancer Research, 1999 - Elsevier
Publisher Summary This chapter focuses on the nature of carcinogenesis and provides an
overview of the progress in this field, and presents successful strategies in
chemoprevention. Chemoprevention is the use of agents to slow the progression of, reverse,
or inhibit carcinogenesis. Chemopreventive agents modulate cancer risk at the molecular,
cellular, tissue, and clinical levels. The mechanisms of these agents are defined by activities
seen at the molecular and cellular levels, while chemopreventive efficacy is evaluated at the …
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