天然膳食化合物作为抗阿尔茨海默病药物的遗传和表观遗传靶标

WO Castillo-Ordoñez, N Cajas-Salazar… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
… ketogenic diet, physical activity, higher education, traumatic brain … One epigenetic mechanism
known as DNA methylation … for the survival, morphogenesis, and neural activity of neurons. …

IKK 調控組蛋白甲基轉移酶G9a 促進癌症發展之探討

李啟恆 - 2014 - tdr.lib.ntu.edu.tw
… human cancers and contributes to the epigenetic silencing of … , MCF-7 and BT549 breast
cancer cells and GST pull down … STAT3 signaling via STAT3 methylation and promotes …

臺灣大數據的公衛應用: 運動對糖尿病患醫療費用與PM2. 5 暴露下SOX2 啟動子甲基化程度的關聯

蘇俊郎 - 2020 - airitilibrary.com
Physical activity (PA) can decrease blood sugar and increase … We evaluated blood DNA
methylation of the SOX2-promoter … Genetic and epigenetic modifications of Sox2 contribute to …

PCDH10 於大腸直腸癌促進細胞凋亡及其基因刪除之探討

廖凱欣 - 2011 - tdr.lib.ntu.edu.tw
… may be regulated by epigenetic modification in CRC cells. … of LOH and promoter
hypermethylation of PCDH10 revealed no … methylated in breast cancer cell lines and in 42.8% …

[HTML][HTML] microRNAs 作為放射治療預後之生物標誌物與miR-148a-3p 於頭頸癌放射敏感度之研究

AL Li - 2022 - ir.lib.ncu.edu.tw
… with a 5-year survival period. Finally, two … into the radiation effect of miR-148a-3p in HNSCC.
The result showed that the expression level of miR-148a-3p was significantly decreased by …

[HTML][HTML] 抑癌基因甲基化与结直肠癌风险因素的研究进展

邓伟, 芦永福 - 世界华人消化杂志, 2018 - wjgnet.com
physical activity, excessive drinking, and unhealthy weight can regulate promoter CGI
hypermethylation, which will help develop new methylation… 的表观遗传学(epigenetics)改变. 抑癌…

长链非编码RNA 在衰老过程中的分子标志及其对衰老相关疾病的显著影响

SAM Sherazi, A Abbasi, MU Abdullah Jamil… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… DNA methylation, and noncoding ribonucleic acid regulation constitute well-known epigenetic
… fresh perspectives on the management, prognosis, and intervention of neurodegenerative …

前列腺癌相關之人類基因甲基轉移酶突變體的結構和生化研究

黃薰禾 - 2023 - tdr.lib.ntu.edu.tw
… Mammalian DNA methylation is an epigenetic modification … into the structure and activity of
these prostate cancer-linked … /3L complexes were largely reduced, supporting that only the H3 …

脑源性神经营养因子在社会压力诱导的抑郁样行为中的脑区特异性作用

M Han, D Zeng, W Tan, X Chen, S Bai, Q Wu… - 中国神经再生研究 …, 2025 - sjzsyj.com.cn
… The epigenetic mechanisms of BDNF in the context of depression include DNA methylation
… Prenatal stress reduces BDNF expression through different epigenetic mechanisms, such …

局部麻醉藥劑促進腫瘤細胞凋亡之研究

張源清 - 2014 - tdr.lib.ntu.edu.tw
… obesity, lack of physical activity, and postmenopausal hormone … of genetic and/or epigenetic
alterations within tumor cells and … and predetermined pattern of DNA methylation. Increased …