[PDF][PDF] Ontology: foundation of biomedical big data and precision medicine research

Y He, H Yu, X Yang, C Shao, W Zhou, Y Zhu… - Chin J …, 2018 - ontochina.org
… Goal: personalized medicine 以个体化医疗为宗旨 o … MedDRA is the default terminology
for vaccine and drug adverse event report 应用:是美国与许多别的国家用于疫苗和药物不良反应…

運用藥物基因表現圖譜和疾病基因標記找尋疾病的藥物治療

WL Yang - 國立臺灣大學資訊工程學系學位論文, 2013 - airitilibrary.com
Drug discovery for diseases is a time-consuming and costly process. Drug repurposing, or
the use of approved drugs … Two ways of drug repurposing strategies are proposed: one is to …

IS-S1-5 指_ H Repurposing of 4-phenylbutyrate for

H Hayashi - jstage.jst.go.jp
… We had better conduct MSI analysis on all distinct tumor lesions to determine patients that
will respond to immunotherapy. These“switching”and“mixing”genetic features would prompt …

重新利用氯硝柳胺来治疗神经系统疾病

S Apolloni, N D'Ambrosi - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
Drug repurposing, or drug repositioning, is a strategy for identifying new uses outside the
scope of the original medical indication for approved drugs, … because the repurposed drug has …

開發基因表現分析方法於藥物探索與癌症治療

CT Huang - 臺灣大學生醫電子與資訊學研究所學位論文, 2019 - airitilibrary.com
drug therapy and repurposing, which will help to substantially reduce the cost and time spent
on drug … in drug research and cancer therapy, achieved with gene expression analysis. …

用于治疗神经障碍的多靶向抗炎药物

A Lui, O Alzayat, T Do, D Perekopskiy… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… Conclusions: In our perspective, repurposing a single FDA-approved multi-targeted kinase
inhibitor would probably lead to new treatments for acute brain injury. The combination of two …

開發基因表現分析方法於藥物探索與癌症治療

黃振綜 - 2019 - tdr.lib.ntu.edu.tw
drug therapy and repurposing, which will help to substantially reduce the cost and time spent
on drug … in drug research and cancer therapy, achieved with gene expression analysis. …

性别, 载脂蛋白E4 和阿尔茨海默氏症: 精准医学时代对药物发现的反思

MD Paranjpe, JK Wang, Y Zhou - 中国神经再生研究(英文版), 2021 - sjzsyj.com.cn
… Accelerating Medicines Partnership. Another powerful and cost-effective drug development
approach is repurposing existing FDA-approved medications. Powerful new computational …

重新使用维拉帕米预防散发性阿尔茨海默病的认知能力下降

HA Ahmed, T Ishrat - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… A repurposed medication has already passed the initial steps required for primary approval,
… can potentially be repurposed for AD as part of a comprehensive therapeutic plan/regimen. …

電腦虛擬篩選人類腫瘤治療藥物

YL Kuo - 國立臺灣大學資訊工程學系學位論文, 2013 - airitilibrary.com
… expense of drug development grows annually, but new drugs approved by FDA … drug-repurposing
strategy in combination with bioinformatics to discover new indications for old drugs. …