[PDF][PDF] 人工智能在药物发现中的应用与挑战
梁礼， 邓成龙， 张艳敏， 滑艺， 刘海春… - Progress in …, 2020 - pps.cpu.edu.cn
… and promising future for the development of medical and pharmaceutical sciences. … 中国药
科大学陆涛教授课题组[3] 的Flt3(Fms-like tyrosine kinase)小分子抑制剂正在 进行I 期临床试验,该…
科大学陆涛教授课题组[3] 的Flt3(Fms-like tyrosine kinase)小分子抑制剂正在 进行I 期临床试验,该…
陶氏症治疗方法的新见解
… trials using kinase inhibitors have not produced encouraging … In addition to the inhibition of
kinases, many small-molecule … -targeting tool by modulating the expression of targeted genes …
kinases, many small-molecule … -targeting tool by modulating the expression of targeted genes …
[PDF][PDF] 肿瘤治疗中小分子激酶抑制剂的研究进展
徐祎春， 韩峻松， 李跃 - 生命科学, 2016 - lifescience.sinh.ac.cn
… one of the intensively pursued targets in development of anti-… mechanism of these small
molecule kinase inhibitors, and … 酪氨酸蛋白激酶(receptor protein tyrosine kinase, RPTK) 和非…
molecule kinase inhibitors, and … 酪氨酸蛋白激酶(receptor protein tyrosine kinase, RPTK) 和非…
抑制腫瘤細胞轉移和成長的分子靶向性先導藥物研發---雜環類先導藥物的演化和多樣式的設計合成(總計畫暨子計畫一)
孫仲銘 - 2007 - ir.lib.nycu.edu.tw
… their respective family of receptor tyrosine kinases (VEGFRs) … 2005, 65, 4389) describing
small-molecule inhibitors affect … one or a few very promising candidates through the parallel or …
small-molecule inhibitors affect … one or a few very promising candidates through the parallel or …
Tau 相关神经退行性疾病的治疗: 靶向分子, 突触和细胞
M Robbins - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… The tyrosine kinase inhibitors are an example of limited … To target the pre-synaptic
compartment, the small molecule … tau and synaptogyrin-3 are promising targets to tackle …
compartment, the small molecule … tau and synaptogyrin-3 are promising targets to tackle …
基于光诱导蛋白质-蛋白质同源相互作用的细胞内信号的光遗传激活
P Huang, Z Zhao, L Duan - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… This strategy has been used for optical activation of receptor tyrosine kinases (RTKs), which
… at targeted subcellular areas and desired time points, which makes them promising tools to …
… at targeted subcellular areas and desired time points, which makes them promising tools to …
蛋白降解靶向嵌合体在小分子药物研发中的机遇与挑战
曾申昕， 黄文海， 沈正荣 - 药学进展, 2020 - pps.cpu.edu.cn
… target protein and E3 ligase, ultimately leading to the target … The promising application and
development of PROTAC has … and challenges in the discovery of small-molecule drugs. [Key …
development of PROTAC has … and challenges in the discovery of small-molecule drugs. [Key …
TrkB 受体激动剂是否是实现脑源性神经营养因子治疗价值承诺的正确工具?
M Zagrebelsky, M Korte - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
Are TrkB receptor agonists the right tool to fulfill the promises for a therapeutic value of the …
Taken together, non-peptide small molecule TrkB agonists have been shown to exert several …
Taken together, non-peptide small molecule TrkB agonists have been shown to exert several …
伊马替尼在脊髓损伤中的转化应用
J Kjell, L Olson - 中国神经再生研究(英文版), 2015 - sjzsyj.com.cn
… after injury has historically focused on promoting nerve growth … imatinib, a small molecule
receptor tyrosine kinase (RTK) … In imatinib we believe we have found an additional promising …
receptor tyrosine kinase (RTK) … In imatinib we believe we have found an additional promising …
巨噬细胞在肺癌转移中的作用
于盼， 周奕阳， 罗斌， 许帆， 田建辉 - 中国肿瘤临床, 2022 - cjco.cn
… Therefore, targeted macrophage prevention and treatment of … and small molecule
inhibitors targeting macrophage … 有研究发现,酪氨酸激酶抑制剂(tyrosine kinase inhibitor,TKI)吉…
inhibitors targeting macrophage … 有研究发现,酪氨酸激酶抑制剂(tyrosine kinase inhibitor,TKI)吉…