… aim of giving inspiration to new drug researchers, expanding the use of small-molecule targeted
… Peptide-based PROTAC degrader of FOXM1 suppresses cancer and decreases GLUT1 …

… in PROTAC technology in terms of protein degradation, drug … -471), oral bioavailable PROTAC
protein degradation agents are … targeted proteins, the determination and optimization of …

… Up to now, most reported CRLs inhibitors are aiming at targeting the F-box family proteins
(… linker to trigger the degradation of target protein. The PROTAC has become a hotspot in the …

… (PROTAC) is an attractive and general strategy for treating cancer based on targeted degradation
… Subsequently, we summarize the development of targeted delivery of PROTAC, such …

… target protein, enabling specific degradation of the target protein … PROTAC分子与POI和E3连接
酶形成三元复合物(POI·PROTAC·… Discovery of covalent ligands via noncovalent docking by …

… , and provide new targeted treatments for drug discovery. In this … orally active PROTAC
degrader of androgen receptor for the … PROTAC-induced BET protein degradation as a therapy for …

… cell lung cancer, NSCLC）常见的突变靶点中，PROTAC技术在… successfully achieved the
effective degradation of kirsten rat … thereby providing a new strategy for the treatment of NSCLC. …

… (PROTAC) technology is a new kind of targeted protein … The use of PROTAC technology to
target the degradation of relevant … 本文将对PROTAC技术进行概述, 并总结PROTAC分子在乳腺…

… Currently, a variety of kinase PROTAC projects have … PROTAC target-ing protein kinases.
Summarize and look forward to the development prospects of targeted protein degradation …

… Discovery of benzotriazolo[4,3-d][1,4]diazepines as orally active … Targeted degradation of
BET proteins in triple-negative … PROTAC-induced BET protein degradation as a therapy for …