… Therefore, we hypothesize that the accumulation of tau PHF-1 in the synaptic
mitochondria could be contributing to the synaptic impairment and cognitive decline in a non-pathological …

… Jinsiwei against synaptic damage is limited. In the current study, we investigated the efficacy
of Jinsiwei on synaptic structure-related proteins drebrin and cofilin, and synaptic function-…

… -associated tau protein and Aβ pathologies, synaptic and neuronal loss are key neuropathologies
of AD brains and are most correlated with cognitive decline in AD patients (de Wilde et …

… pathological pathways, synaptic dysfunctions, such as synapses loss and deficits in
synaptic … of epileptiform abnormalities and seizures in Alzheimer disease. Neurology 95:e2259-2270…

… impact of hyperbaric oxygen therapy on Alzheimer's disease|Airiti Library 華藝線上圖書館 …
mitochondrial and synaptic functions, thereby accelerating the progression of AD. Research …

… tangles and synapse loss, are the principal pathological hallmarks of Alzheimer’s disease.
Amyloid β … , and alteration of synaptic functions related with learning and memory. Parkinson’s …

… disorders – Alzheimer’s and Parkinson’s diseases – are characterized by synaptic …
Petersen R (2018) How early can we diagnose Alzheimer disease (and is it sufficient)? The …

… Importantly, the removal of astrocytic ApoE4 decreased tau-induced synaptic loss and
microglial phagocytosis of synaptic elements, suggesting a key role for astrocytic ApoE in synaptic …

… association between synaptic loss in the neocortex and limbic system and the progression
of cognitive impairment in patients … The normal function, structure, and number of synapses …

… This review provided insights on mitochondrial dysfunction/mutations … of Alzheimer’s disease,
Huntington’s disease, and epilepsy with a special focus on Parkinson’s disease pathology. …