… The colonystimulating factor-1 receptor is expressed by myeloid … Sustained and exacerbated
microglial activation has negative … inhibitors may target several cell populations other than …

Targeting colony stimulating factor 1 receptor to prevent … a specific colony stimulating factor
1 receptor (CSF-1R) inhibitor … In addition, macrophages may play different roles in different …

… Granulocyte macrophage colony stimulating factor (GM-CSF) is increased in patients … drug
administration has a strong rationale. Furthermore, clinical trials with immunotherapy targeting …

… Colony stimulating factor 1 receptor (CSF1R) is a tyrosine … target for treatments to halt
neurodegeneration. Several studies have shown that administration of various CSF1R inhibitors …

… ) motif ligand 21 and colony-stimulating factor 1, which in turn … macrophages, including
microglia, express this receptor. It … In conclusion, P2X4 receptors are an emerging drug target for …

… macrophage proliferation through colony stimulating factor-1 … inhibitor is induced by CSF1
and regulates the macrophage … into this targeting strategy, given macrophage subsets are …

… [Abstract] Macrophage colony stimulating factor receptor (c-… Many small molecular inhibitors
targeting c-Fms are under research … colony stimulating factor 1 receptor inhibitor PLX3397 in …

… the exact role of microglial activation in neural regeneration and … (D) Colony-stimulating factor
1 receptor inhibitor PLX3397 … Nevertheless, recent advances in genetically targeted loss-of…

… targets for axonal regeneration. Key Words: fibrotic scar; glial scar; inflammation; … nerve and
retina microglia depletion studies with colony stimulation factor-1 receptor inhibitor PLX5622 …

… In addition to ABL and SRC inhibitors, other tyrosine kinases are potential therapeutic
targets in neurodegeneration. For example, colony stimulating factor 1 receptor (CSF1R), c-KIT …