Jingfang Granules (荆防颗粒) alleviates bleomycin-induced acute lung injury through regulating PI3K/Akt/mTOR signaling pathway

X Sun, H Xiang, Z Liu, H Xiao, X Li, W Gong… - Journal of …, 2024 - Elsevier
signaling pathway, indicating that the changes of above … and used these components to
identify potential targets and signal … that the target of JF in treating ALI is enriched in the PI3K/Akt

[HTML][HTML] 基于miRNA 表达谱解析细粒棘球蚴病患者体内Th17/Treg 失衡机制

鲁迪, 宋佳卉, 马子建, 张鹏越, 许磊, 韦川, 陈颖… - 中国血吸虫病防治 …, 2022 - zgxfzz.com
… highest fold changes, there were 3 miRNAs that had a potential for target regulation of RORC,
and 15 miRNAs that had a potential to target the PI3KAkt and mTOR signaling pathways. …

… Decoction (加味苓桂术甘汤) Ameliorates Glycolipid Metabolism and Inflammation via PI3K-Akt/mTOR-S6K1/AMPK-PGC-1 α Signaling Pathways in Obese Type 2 …

J Sun, L Shi, F Wang, J Qin, B Ke - Chinese journal of integrative medicine, 2020 - Springer
alteration of phosphatidylinositol 3 kinase (PI3K)protein kinase B (PKB or Akt)/the mammalian
target of rapamycin (mTOR)-… disorders maybe a potential target to prevent the occurrence …

[HTML][HTML] Efficacy of Ganshuang granules (肝爽颗粒) on non-alcoholic fatty liver and underlying mechanism: a network pharmacology and experimental verification

ZHI Guoguo, S Bingjie, T Zheng… - Journal of Traditional …, 2024 - ncbi.nlm.nih.gov
potential therapeutic targets may be involved in PI3K/AKT … effect of GSG on the PI3K/AKT
signaling pathway, which was … ELISA kit was also used to detect the changes in the expression …

用于获得差别调节髓鞘形成的治疗剂的下一代药物连接图

K Azim, AD Rivera, AM Butt - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… for hands-on investigators where the key target genes observed in this analysis can be …
target genes can be used for identifying pathways altered, their mechanisms, and any potential

[PDF][PDF] 我们可以通过阻止microRNA 表达中年龄相关性降低来治疗神经变性疾病吗?

IA Vinnikov, A Domanskyi - 中国神经再生研究(英文版), 2017 - sjzsyj.com.cn
… PD is attributed to genetic mutations, mitochondrial … targets (TarBase v7.0) identified
several miRNAs targeting both PTEN and Bim, and thus potentially activating Akt/PI3K pathway

[HTML][HTML] Network pharmacology and experimental validation to reveal the pharmacological mechanisms of Sini decoction (四逆汤) against renal fibrosis

W Yan, D Fanying, LIU Shiqi… - Journal of Traditional …, 2024 - ncbi.nlm.nih.gov
… in Rf treatment, their potential targets, and signaling pathways. Additionally, pharmacological
… -β1 in this signaling pathway, which can improve hormone disorders, inhibit inflammation, …

Tounong Powder (透脓散) extracts induce G1 cell cycle arrest and apoptosis in LoVo cells

L Fang, S Liu, R Wang, S Hu, W Ju, C Li - Chinese Journal of Integrative …, 2016 - Springer
… -treating prescriptions could have potential effects for treating … from upstream signaling
pathways by genetic alterations in … inhibit multiple targets of the PI3K/AKT pathway, which may …

Lin28: 中枢神经系统再生和修复的治疗靶点

S Wang, S Li - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… deficits in patients with neurological disorders. Currently, there is … the expression of the
targeted gene in various projection … this gene has the potential to repair multiple peripheral tissue …

基于网络药理学从铁死亡途径研究补阳还五汤调控缺血性脑卒中的作用机制

赵冯岩, 杨浩澜, 朱炎贞, 林美妤… - 湖南中医药大学 …, 2021 - hnzyydxxb.hnucm.edu.cn
targets and module genes were enriched by KEGG pathway in KOBAS 3.0. Western blot were
used to detect the expression of p-PI3K, PI3K, p-Akt, Akt, p… Results There were 10 potential