探討類核體相關蛋白在R-loop 誘發之基因不穩定性及抗藥性機制中所扮演的角色

CH Lin - 國立臺灣大學微生物學研究所學位論文, 2017 - airitilibrary.com
co-transcriptional R-loop formation such as RNase H enzyme to dissolve specifically the
RNA/DNA hybrid. … they may contribute to maintenance of genome integrity and play a potential …

锌指蛋白ZPR1: 拯救脊髓性肌萎缩症的运动神经元存活依赖调节剂

J Cuartas, L Gangwani - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… ZPR1 may play a role in the regulation of pre-mRNA transcription by contributing to … co-transcriptional
R-loops. Accumulation of R-loops is a major cause of DNA damage and genomic

[PDF][PDF] R 环的形成及其在疾病中的作用研究进展

杜志鹏, 杨彦勇, 蔡建明 - 温州医科大学学报, 2022 - xb.wmu.edu.cn
… Identification of early replicating fragile sites that contribute to genome instability[J]. Cell, 2013,
Cotranscriptional R-loops are the main cause of estrogeninduced DNA damage[J]. Elife, …

微小RNA 在肌萎缩性侧索硬化动物模型中的表达及潜在的治疗方法

B Martinez, PV Peplow - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
gene with disease-associated expansion (~100–1000 repeats) exhibited pathological features
observed in C9orf72 expansion patients including widespread RNA … the importance and …